Evidence map›Paper›PMID 31884960›Full record

SynthesisBMC musculoskeletal disorders2019

Risk factors associated with osteonecrosis of femoral head after internal fixation of femoral neck fracture:a systematic review and meta-analysis.

Jing-Li Xu, Zheng-Rong Liang, Bing-Lang Xiong, Qi-Zhao Zou, Tian-Ye Lin, Peng Yang, Da Chen, Qing-Wen Zhang

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 5 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 5 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  11. Association between screw angulation and union after inverted-triangle cannulated screw fixation of femoral neck fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jing-Li XuThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zheng-Rong LiangThe First Clinical Medicine School of Jinan University, Guangzhou, China.
Bing-Lang XiongThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qi-Zhao ZouThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Tian-Ye LinThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Peng YangThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Da ChenThe Sun Yat-sen University Cancer Center, Guangzhou, China. chenda1@sysucc.org.cn.
Qing-Wen ZhangThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, No.16, Ji Chang Road, Baiyun District, Guangzhou, 510405, China. zh__qwen@163.com.ORCID http://orcid.org/0000-0002-5417-2970
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CNJinan University · CNSun Yat-sen University · CN

Funding

Natural Science Foundation of China 81704101Natural Science Foundation of Guangdong 2015A030313353Science and Technology Project of Guangdong 2013A032500009
6 · The paper itself

Abstract

backgroundAlthough the risk factors associated with osteonecrosis of femoral head (ONFH) after internal fixation of femoral neck fracture (IFFNF) have been frequently reported, the results remain controversial. Therefore, its related risk factors were systematically evaluated and meta-classified in this study.

methodsLiterature on risk factors of ONFH caused by IFFNF was retrieved in PubMed, Embase and Cochrane Library due June 2019. Review Manager 5.3 software was applied to data synthesis, and Stata 13.0 software was adopted for analyses of publication bias and sensitivity.

resultsA total of 17 case-control studies with 2065 patients were included. The risk of ONFH after IF was 0.40-fold higher in patients with Garden III-IV FNF than that in patients with Garden I-II (OR: 0.40, 95%CI: 0.29-0.55). The risk of OFNH with retained IF was uplifted by 0.04 times (OR: 0.04, 95%CI: 0.02-0.07). There was nonsignificant relationship between gender and ONFH after IFFNF (OR: 1.27, 95%CI: 0.84-1.94). Moreover, ONFH after IFFNF presented no association with age (OR:1.66, 95%CI: 0.89-3.11), injury-operation interval (OR:1.29, 95%CI: 0.82-2.04), fracture reduction mode (OR:1.98, 95%CI: 0.92-4.26), preoperative traction (OR:1.69, 95%CI: 0.29-9.98) and mechanism of injury (OR:0.53, 95%CI: 0.06-4.83). Egger's and Begg's tests indicated a publication bias (P = 0.001).

conclusionIt was demonstrated that Garden classification and retained IF were important influencing factors of ONFH after IFFNF. Gender, age, injury-operation interval, fracture reduction mode, preoperative traction and the mechanism of ONFH were irrelevant to the complication.

Indexed as

Age FactorsFemaleFemoral Neck FracturesFemur Head NecrosisFracture Fixation, InternalHumansMalePostoperative ComplicationsRisk FactorsSex FactorsTime FactorsFemoral neck fractureInternal fixationOsteonecrosis of femoral headRisk factorsSystematic review

Identifiers

PMID31884960
PMCPMC6935498
OpenAlexW2998436926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.