Evidence map›Paper›PMID 31884951›Full record

ArticleBMC musculoskeletal disorders2019

Diagnostic potential of ultrasound in carpal tunnel syndrome with different etiologies: correlation of sonographic median nerve measures with electrodiagnostic severity.

Basant Elnady, Elsayed M Rageh, Tohamy Ekhouly, Sabry M Fathy, Mohamed Alshaar, El Saeed Fouda, Mohammed Attar, Ahmed M Abdelaal, Ahmed El Tantawi, Mohammed M Algethami and 1 more

Registry-linked trialOpen access · goldAbstract readValidation Study
In one paragraph

Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06045013 (Comparison of the Efficacy Between Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone Injection in Patients With Carpal Tunnel Syndrome), which is not on this map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06045013 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

Comparison of the Efficacy Between Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone Injection in Patients With Carpal Tunnel Syndrome: a Prospective, Randomized Double-blind Clinical Trial.

TypeinterventionalSponsorGeneral and Veteran Hospital Croatian Pride KninRan2023 to 2026Enrolled70ConditionsCarpal Tunnel SyndromeArms5% dextrose injection, 5% dextrose injections with methylprednisolone acetate 40 mg/ml
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 51 citations in OpenAlex.

  1. Evaluation of Splint and Exercise Interventions for Carpal Tunnel Syndrome: Insights from Ultrasonographic Measurements.Medical science monitor : international medical journal of experimental and clinical research · 2024
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  20. Hand-Wrist Disorders in Chainsaw Operators: A Follow-Up Study in a Group of Italian Loggers.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 4 countries.

Basant ElnadyDepartment of Rheumatology, Rehabilitation and Physical Medicine, Benha University, Benha, Egypt. basantelnady@gmail.com.ORCID http://orcid.org/0000-0002-5908-0151
Elsayed M RagehDepartment of Rheumatology, Rehabilitation and Physical Medicine, Tanta University, Tanta, Egypt.
Tohamy EkhoulyDepartment of Radiology, Benha University, Benha, Egypt.
Sabry M FathyDepartment of Neurology, Al Azhar University, Al Azhar, Egypt.
Mohamed AlshaarDepartment of Neurology, Al Azhar University, Al Azhar, Egypt.
El Saeed FoudaDepartment of Pediatrics, Menoufia University, Shebeen El-Kom, Egypt.
Mohammed AttarDepartment of Internal Medicine, Al Hada Forces Hospital, Alhada, Saudi Arabia.
Ahmed M AbdelaalDepartment of Neurosurgery, Salford Royal NHS Foundation Trust, Salford, England.
Ahmed El TantawiDepartment of Neurosurgery, Ain Shams University, Ain Shams, Egypt.
Mohammed M AlgethamiDepartment of Internal Medicine, Al Hada Forces Hospital, Alhada, Saudi Arabia.
David BongInstituto Poal de Reumatologia, University of Barcelona, Barcelona, Spain.
Al-Azhar University · EGArmed Forces Hospital · SABenha University · EGAin Shams University · EGMenoufia University · EGSalford Royal NHS Foundation Trust · GBTanta University · EGUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarpal tunnel syndrome (CTS) is the commonest entrapment neuropathy. The aim of this study was to assess the accuracy and validity of high resolution musculoskeletal ultrasound (US) in the diagnosis of CTS in the Saudi population.

methodsSixty patients were diagnosed clinically to have CTS involving 89 wrists that were confirmed by neurophysiologic studies. Each affected wrist was characterized as idiopathic or associated with either diabetes mellitus or hypothyroidism and were assigned a severity grade based on results of neurophysiologic studies. Seventy-six healthy wrists from fifty age, sex and BMI matched healthy subjects were included in the control group. High resolution ultrasound (US) was performed to assess median nerve cross sectional area distal (CSAd) at the entry to the carpal tunnel and proximally (CSAp) at the level of pronator quadratus muscle with a further calculation of their difference (ΔCSA) and their mean average or CSAd+CSAp/2 (CSApd).

resultsThere was a significant difference between both groups regarding mean ± SD of CSAd, CSAp, ∆CSA, and CSApd (p = 0.0001). A positive significant correlation was also found between the CSAd, ∆ CSA and the CSApd measurements with neurophysiologic severity grade of CTS (P = 0.001). A ∆CSA threshold of 2.5 mm

conclusionHigh resolution ultrasound is a valid and accurate diagnostic modality in carpal tunnel syndrome and correlated to CTS severity. A ∆CSA greater than 2.5 mm

Indexed as

AdultCarpal Tunnel SyndromeCase-Control StudiesElectrodiagnosisFemaleHumansMaleMedian NerveMiddle AgedNeural ConductionSensitivity and SpecificitySeverity of Illness IndexUltrasonographyCarpal tunnel syndromeMedian nerveUltrasound

Identifiers

PMID31884951
PMCPMC6935486
OpenAlexW2998198430

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.