ReviewCurrent pediatric reviews2020
Preeclampsia Emerging as a Novel Risk Factor for Cardiovascular Disease in the Offspring.
Review in Current pediatric reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 34 citations in OpenAlex.
- Decidualization potential of endometrial mesenchymal stem cells and their role in reproductive health.Reproductive biology and endocrinology : RB&E · 2026Review
- Short- and Long-Term Clinical Outcomes of Preeclampsia in Women and Their Neonates in Pregnancies With and Without HIV Infection.International journal of hypertension · 2026Review
- Article
- Elevated Blood Pressure in Newborns From Hypertensive Disorders of Pregnancy During the Immediate Postnatal Period.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Clinical implications of a history of pre-eclampsia in women with type two diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association · 2025Article
- Pharmacologic and endotoxic reprogramming of renal vasodilatory, inflammatory, and apoptotic blemishes in weaning preeclamptic rats.Scientific reports · 2025Article
- Insights into the Global and Mexican Context of Placental-Derived Pregnancy Complications.Biomedicines · 2025Review
- Quercetin alleviates endothelial dysfunction in preeclampsia by inhibiting ferroptosis and inflammation through EGFR binding.Communications biology · 2025Article
- In vitro examination of Piezo1-TRPV4 dynamics: implications for placental endothelial function in normal and preeclamptic pregnancies.American journal of physiology. Cell physiology · 2025Article
- [The association between preterm birth and hypertension].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Review
- Interdependence of placenta and fetal cardiac development.Prenatal diagnosis · 2024Review
- Early Fetal Growth Restriction with or Without Hypertensive Disorders: a Clinical Overview.Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Potential Roles of microRNAs for Assessing Cardiovascular Risk in Pre-Eclampsia-Exposed Postpartum Women and Offspring.International journal of molecular sciences · 2023Review
- Endogenous Digitalis-like Factors as a Key Molecule in the Pathophysiology of Pregnancy-Induced Hypertension and a Potential Therapeutic Target in Preeclampsia.International journal of molecular sciences · 2023Review
- Article
- Clinical characteristics and treatment patterns of pregnant women with hypertension in primary care in the Federal Capital Territory of Nigeria: cross-sectional results from the hypertension treatment in Nigeria Program.BMC pregnancy and childbirth · 2023Article
- Preterm newborns exposed to early-onset preeclampsia have altered postnatal Tumor Necrosis Factor-related apoptosis-inducing ligand trends versus controls.Pediatric research · 2023Article
- Impact of Adverse Gestational Milieu on Maternal Cardiovascular Health.Endocrinology · 2023Review
- Meta-Analysis of Cardiovascular Risk Factors in Offspring of Preeclampsia Pregnancies.Diagnostics (Basel, Switzerland) · 2023Review
- Analysis of Pregnancy Complications and Epigenetic Gestational Age of Newborns.JAMA network open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPreeclampsia is a pregnancy specific disorder which affects 2%-8% of all gestations and is associated with high maternal, fetal and neonatal morbidity and mortality worldwide. There is no "cure" for the disease except for early delivery of the fetus and placenta, however leaving preeclampsia a long term health risk both for mothers and infants.
aimThe aim of the study is to review currently available information linking preclampsia to longterm cardiovascular complications in infants and children.
resultsCurrently, there is evidence of predisposition to cardiovascular disease, and a higher incidence of cardiovascular risk factors among children born to preeclamptic mothers. Both in experimental models and human epidemiological studies it is now clear that the infants of pregnancies complicated by preeclampsia have an increased risk of developing high blood pressure and double the risk of stroke in later life. Preeclampsia is consistently associated with higher blood pressure and body mass index as early as 4-10 years of age. Also there is some evidence of higher cardiovascular risk in adults exposed to maternal hypertensive disorders of pregnancy. It seems that preeclampsia has an impact on the cardiovascular system independent of preterm birth and is associated with endothelial dysfunction, increased carotid intima media thickness and reductions in cardiac function that cannot be accounted for by prematurity alone.
conclusionTaking into consideration the currently available evidence, it can now be suggested that preeclampsia is linked to adverse effects on the cardiometabolic health of the infant. Understanding the relationship between preeclampsia and cardiovascular disease will allow for implementation of early interventions to prevent or delay the onset of adverse events in this high risk population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.