Evidence map›Paper›PMID 31884902›Full record

ArticleStroke2020

Implementation of High-Intensity Stepping Training During Inpatient Stroke Rehabilitation Improves Functional Outcomes.

Jennifer L Moore, Jan E Nordvik, Anne Erichsen, Ingvild Rosseland, Elisabeth Bø, T George Hornby, FIRST-Oslo Team

6 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 58 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 4 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04870619 completednot on this mapstarted 2021, after this paper: background citation

FOCUSED INTENSIVE REPETITIVE STEP TRAINING - Long-term Follow-up of High Intensity Stepping Training After Stroke in Oslo (FIRST-Oslo - Long-term)

TypeobservationalSponsorOslo University HospitalRan2021 to 2023Enrolled69ConditionsStrokeArmsHigh Intensity Gait Training
NCT04973852 nacompletednot on this mapstarted 2021, after this paper: background citation

High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2021 to 2023Enrolled11ConditionsSpinal Cord InjuriesArmsEkso
NCT05622786 naterminatednot on this mapstarted 2022, after this paper: background citation

Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients

TypeinterventionalSponsorCarilion ClinicRan2022 to 2023Enrolled11ConditionsTraumatic Brain Injury, Gait Disorders, NeurologicArmsHIGT - physical rehab, Low intensity physical therapy
NCT05650606 naterminatednot on this mapstarted 2023, after this paper: background citation

Inpatient Rehabilitation and Post-Discharge Outcomes of Patients With Stroke Participating in High Intensity Gait Training

TypeinterventionalSponsorSunnyview Rehabilitation HospitalRan2023 to 2023Enrolled2ConditionsCerebral Vascular AccidentArmsHigh Intensity Gait Training, Conventional Therapy
NCT05727930 narecruitingnot on this mapstarted 2023, after this paper: background citation

Variable Intensive Early Walking Post-Stroke -2 (VIEWS-2)

TypeinterventionalSponsorIndiana UniversityRan2023 to 2028Enrolled100ConditionsStrokeArmsHigh-intensity, task-specific (i.e., walking) interventions, High-intensity, non-specific physical therapy interventions, Low-intensity, task-specific physical therapy interventions, Low-intensity, non-specific physical therapy interventions
NCT06867081 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of a Customized Digital Platform to Increase Coordination of Care and Uptake of Evidence-based Practices: a Protocol for a Stepped-wedge Cluster Randomized Trial in Quebec

TypeinterventionalSponsorCentre for Interdisciplinary Research in Rehabilitation of Greater MontrealRan2025 to 2029Enrolled962ConditionsAquired Brain Injury, Traumatic Brain Injuries, Stroke, Cardiovascular DiseasesArmsThe intervention will be the BRILLIANT Platform, an online platform which provides five Modules aimed at increasing coordination of care and direct rehabilitation time
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 120 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Exoskeletal-Assisted Training in Veterans With Chronic Stroke: A Pilot Study.Archives of rehabilitation research and clinical translation · 2026
    Article
  17. Article
  18. Home-Based Gait Interventions for Adults with Stroke: A Scoping Review.Archives of rehabilitation research and clinical translation · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jennifer L MooreFrom the Regional Center of Knowledge Translation in Rehabilitation, Sunnaas Rehabilitation Hospital, Oslo/Nesodden, Norway (J.L.M.).
Jan E NordvikCatoSenteret Rehabilitation Hospital, Son, Norway (J.E.N.).
Anne ErichsenSection of Physiotherapy, Department of Medicine, Oslo University Hospital, Norway (A.E., E.B.).
Ingvild RosselandCity of Oslo, Reinforced Interdisciplinary Rehabilitation Aker, Norway (I.R.).
Elisabeth BøSection of Physiotherapy, Department of Medicine, Oslo University Hospital, Norway (A.E., E.B.).
T George HornbyDepartment of Physical Medicine and Rehabilitation, Indiana University, Indianapolis (T.G.H.).
FIRST-Oslo Team
Oslo University Hospital · NOIndiana University – Purdue University Indianapolis · USSunnaas sykehus · NO

Funding

Locomotor Recovery and Compensation Post-strokeR01NS118009 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI Thomas George Hornby · 2021 to 2026
$2.0M
Sympathetic-somatomotor coupling in human SCIR01NS079751 · NINDS · MARQUETTE UNIVERSITY · PI HORNBY, THOMAS GEORGE, SCHMIT, BRIAN D · 2013 to 2017
$1.6M
NINDS NIH HHS R01 NS079751NINDS NIH HHS R01 NS118009
6 · The paper itself

Abstract

Background and Purpose- Therapeutic strategies that capitalize on the intrinsic capacity for neurological recovery early poststroke to improve locomotion are uncertain. Emerging data suggest that task-specific stepping practice provided at higher cardiovascular intensities may be critical dosage parameters that could maximize locomotor recovery. The purpose of this investigation was to determine the comparative effectiveness of providing high-intensity training on locomotor capacity early poststroke as compared with usual care. Methods- A quasi-experimental design was used to compare changes in stepping activity (StepWatch), walking, and balance outcomes during usual care (n=56) versus high-intensity stepping intervention (n=54) in inpatient stroke patients. Primary outcomes assessed weekly included self-selected and fastest gait speed, 6-minute walk test, and the Berg Balance Scale, with secondary outcomes of Swedish Postural Assessment Scale for Stroke-Norwegian version, Functional Ambulation Category, 30-s sit-to-stand, strength (average manual muscle testing), and Barthel Index. Regression analyses identified relationships between demographics, baseline function, and training activities (steps per day; duration achieved, 70%-85% maximum heart rates) and primary outcomes at discharge. Results- Following implementation of high-intensity stepping, average steps per day (5777±2784) were significantly greater than during usual care (3917±2656;

Indexed as

Exercise TherapyStroke RehabilitationFemaleGaitHumansInpatientsMaleMiddle AgedOutcome Assessment, Health CarePostural BalanceRecovery of FunctionStrokeWalkingexerciseimplementation sciencelocomotionrehabilitationwalkingwalk test

Identifiers

PMID31884902
PMCPMC7034641
OpenAlexW2997352565

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.