Evidence map›Paper›PMID 31884521›Full record

ArticleJournal of ophthalmic inflammation and infection2019

Topographic correlation between multifocal electroretinography, microperimetry, and spectral-domain optical coherence tomography of the macula in patients with birdshot chorioretinopathy.

Rubbia Afridi, Aniruddha Agarwal, Nam V Nguyen, Muhammad Hassan, Mohammad Ali Sadiq, Quan Dong Nguyen, Yasir J Sepah

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rubbia AfridiOcular Imaging Research and Reading Center, Menlo Park, CA, USA.
Aniruddha AgarwalAdvanced Eye Center, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Nam V NguyenOcular Imaging Research and Reading Center, Menlo Park, CA, USA.
Muhammad HassanByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Mohammad Ali SadiqOcular Imaging Research and Reading Center, Menlo Park, CA, USA.
Quan Dong NguyenOcular Imaging Research and Reading Center, Menlo Park, CA, USA.
Yasir J SepahOcular Imaging Research and Reading Center, Menlo Park, CA, USA. yjs@stanford.edu.ORCID http://orcid.org/0000-0002-0104-6284
Smith-Kettlewell Eye Research Institute · USPost Graduate Institute of Medical Education and Research · INSRI International · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo correlate the findings of retinal function with multifocal electroretinogram (mfERG), microperimetry (MP), and structural assessments with spectral-domain optical coherence tomography (SD-OCT) in topographically corresponding areas of the macula of patients with birdshot chorioretinopathy (BSCR).

methodsPatients diagnosed with BSCR by clinical and imaging findings were included in the study. The mfERG was performed using 61 hexagon stimulus patterns grouped into 5 rings (Diagnosys Inc., USA). Individual responses [N1-P1 amplitudes in nanovolt (NV)/degree

resultsSixteen eyes of eight patients were included in the study (mean age, 59.87 ± 10.01 years; range, 41-73 years). The amplitudes and the implicit times on mfERG and retinal sensitivities on MP were decreased for each of the 19 hexagons. Considering retinotopically matched points, there was correlation between the retinal sensitivities and mfERG implicit times and response amplitudes in all three rings. The thickness of the retinal pigment epithelium showed modest correlation with the mfERG parameters (ρ = 0.29; p = 0.04). The structural changes on SD-OCT, such as IS-OS disruption, were associated with changes in the mfERG trace arrays.

conclusionsThe structural and functional assessments in retinae of eyes with BSCR suggest that each imaging tool may be capturing unique aspects of retinal dysfunction. Multimodal imaging may allow detailed analyses of retinal damage at various corresponding loci. These findings are important when considering the use of these techniques in BSCR.

Indexed as

Birdshot chorioretinopathyMicroperimetryMultifocal electroretinogramMultimodal imagingOptical coherence tomography

Identifiers

PMID31884521
PMCPMC6935379
OpenAlexW2997794320

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.