Evidence map›Paper›PMID 31884388›Full record

ReviewMolecular immunology2020

Myeloid-driven mechanisms as barriers to antitumor CD8

Sean H Colligan, Stephanie L Tzetzo, Scott I Abrams

Open access · greenAbstract readReview
In one paragraph

Review in Molecular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Neuropeptide Y as a Neuro-Immune Checkpoint in Cancer.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Targeting ROS-sensing Nrf2 potentiates anti-tumor immunity of intratumoral CD8Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sean H ColliganDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY, 14623, United States.
Stephanie L TzetzoDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY, 14623, United States.
Scott I AbramsDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY, 14623, United States. Electronic address: scott.abrams@roswellpark.org.
Roswell Park Comprehensive Cancer Center · US

Funding

MULTIDISCIPLINARY APPROACHES TUMOR IMMUNOLOGYT32CA085183 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Scott I. Abrams · 2001 to 2026
$3.1M
Mechanisms Underlying Functional Programs of Tumor-Associated MacrophagesR01CA172105 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI ABRAMS, SCOTT I. · 2015 to 2019
$2.0M
Transcriptional Control of Macrophage-Mediated Mechanisms of MetastasisF31CA243304 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI TZETZO, STEPHANIE · 2019 to 2021
$91k
Regulation of IRF8 in PMN-MDSC Development Within the Bone Marrow MicroenvironmentF31CA228396 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI COLLIGAN, SEAN · 2018 to 2020
$89k
NCI NIH HHS F31 CA228396NCI NIH HHS F31 CA243304NCI NIH HHS R01 CA172105NCI NIH HHS T32 CA085183
6 · The paper itself

Abstract

The adaptive immune system is essential for host defense against pathogenic challenges, and a major constituent is the CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesHumansImmunotherapyMyeloid CellsNeoplasmsT-Lymphocytes, CytotoxicCD8(+) T cellsImmune suppressionImmunotherapyMacrophagesMyeloid-derived suppressor cells

Identifiers

PMID31884388
PMCPMC6994167
OpenAlexW2997544519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.