Evidence map›Paper›PMID 31883846›Full record

ReviewThe Journal of allergy and clinical immunology2020

Artificial intelligence approaches using natural language processing to advance EHR-based clinical research.

Young Juhn, Hongfang Liu

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 6 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 6 syntheses or guidelines pooled it, 279 citations in OpenAlex.

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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Young JuhnPrecision Population Science Lab, Division of Community Pediatric and Adolescent Medicine, Department of Pediatric and Adolescent Medicine, Rochester, Minn; Division of Allergy, Department of Medicine, Mayo Clinic, Rochester, Minn. Electronic address: juhn.young@mayo.edu.
Hongfang LiuDivision of Digital Health, Department of Health Sciences Research, Mayo Clinic, Rochester, Minn.
Department of Medical Sciences · BY

Funding

Identification and characterization of children with asthma-associated comorbidities through computational and immune phenotypingR01HL126667 · NHLBI · MAYO CLINIC ROCHESTER · PI JUHN, YOUNG J, LIU, HONGFANG · 2015 to 2022
$4.3M
Enhanced Ascertainment of Asthma Status Via Natural Language ProcessingR21AI116839 · NIAID · MAYO CLINIC ROCHESTER · PI JUHN, YOUNG J, WU, STEPHEN TZE-INN · 2015 to 2016
$437k
NHLBI NIH HHS R01 HL126667NIAID NIH HHS R21 AI116839
6 · The paper itself

Abstract

The wide adoption of electronic health record systems in health care generates big real-world data that open new venues to conduct clinical research. As a large amount of valuable clinical information is locked in clinical narratives, natural language processing techniques as an artificial intelligence approach have been leveraged to extract information from clinical narratives in electronic health records. This capability of natural language processing potentially enables automated chart review for identifying patients with distinctive clinical characteristics in clinical care and reduces methodological heterogeneity in defining phenotype, obscuring biological heterogeneity in research concerning allergy, asthma, and immunology. This brief review discusses the current literature on the secondary use of electronic health record data for clinical research concerning allergy, asthma, and immunology and highlights the potential, challenges, and implications of natural language processing techniques.

Indexed as

Allergy and ImmunologyElectronic Health RecordsNatural Language ProcessingResearch DesignHumansalgorithmsallergyartificial intelligenceasthmadata miningEHRsimmunologyinformaticsmachine learningnatural language processing

Identifiers

PMID31883846
PMCPMC7771189
OpenAlexW2997514453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.