Evidence map›Paper›PMID 31883122›Full record

ArticleMedical physics2020

Automatic coronary artery plaque thickness comparison between baseline and follow-up CCTA images.

Qing Cao, Alexander Broersen, Pieter H Kitslaar, Mingyuan Yuan, Boudewijn P F Lelieveldt, Jouke Dijkstra

Abstract readComparative Study
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qing CaoDivision of Image Processing, Department of Radiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands.
Alexander BroersenDivision of Image Processing, Department of Radiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands.
Pieter H KitslaarMedis Medical Imaging System BV, Leiden, The Netherlands.
Mingyuan YuanZhoupu Hospital, Shanghai University of medicine & health Science, Shanghai, China.
Boudewijn P F LelieveldtDivision of Image Processing, Department of Radiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands.
Jouke DijkstraDivision of Image Processing, Department of Radiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands.

Funding

China Scholarship Council 201406090166
6 · The paper itself

Abstract

purposeCurrently, coronary plaque changes are manually compared between a baseline and follow-up coronary computed tomography angiography (CCTA) images for long-term coronary plaque development investigation. We propose an automatic method to measure the plaque thickness change over time.

methodsWe model the lumen and vessel wall for both the baseline coronary artery tree (CAT-BL) and follow-up coronary artery tree (CAT-FU) as smooth three-dimensional (3D) surfaces using a subdivision fitting scheme with the same coarse meshes by which the correspondence among these surface points is generated. Specifically, a rigid point set registration is used to transform the coarse mesh from the CAT-FU to CAT-BL. The plaque thickness and the thickness difference is calculated as the distance between corresponding surface points. To evaluate the registration accuracy, the average distance between manually defined markers on clinical scans is calculated. Artificial CAT-BL and CAT-FU pairs were created to simulate the plaque decrease and increase over time.

resultsFor 116 pairs of markers from nine clinical scans, the average marker distance after registration was 0.95 ± 0.98 mm (two times the voxel size). On the 10 artificial pairs of datasets, the proposed method successfully located the plaque changes. The average of the calculated plaque thickness difference is the same as the corresponding created value (standard deviation ± 0.1 mm).

conclusionsThe proposed method automatically calculates local coronary plaque thickness differences over time and can be used for 3D visualization of plaque differences. The analysis and reporting of coronary plaque progression and regression will benefit from an automatic plaque thickness comparison.

Indexed as

Computed Tomography AngiographyAutomationCoronary Artery DiseaseHumansImage Processing, Computer-AssistedPlaque, AtheroscleroticSignal-To-Noise Ratiobaseline and follow-upcoronary arteriescoronary computed tomography angiographyplaque thicknessvisualization

Identifiers

PMID31883122
PMCPMC7079078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.