ArticleEJNMMI physics2019
Time-modified OSEM algorithm for more robust assessment of left ventricular dyssynchrony with phase analysis in ECG-gated myocardial perfusion SPECT.
Article in EJNMMI physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- The feasibility ofQuantitative imaging in medicine and surgery · 2022Article
- Phase analysis of gated myocardial perfusion SPECT and cardiac resynchronization therapy: The good, the bad, and the ugly.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Correlation analysis of epicardial adipose tissue volume quantified by computed tomography images and coronary heart disease under optimized reconstruction algorithm.Pakistan journal of medical sciences · 2021Article
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4 authors.
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Abstract
backgroundIn ordered subsets expectation maximization (OSEM) reconstruction of electrocardiography (ECG)-gated myocardial perfusion single-photon emission computed tomography (SPECT), it is often assumed that the image acquisition time is constant for each projection angle and ECG bin. Due to heart rate variability (HRV), this assumption may lead to errors in quantification of left ventricular mechanical dyssynchrony with phase analysis. We hypothesize that a time-modified OSEM (TOSEM) algorithm provides more robust results.
methodsList-mode data of 44 patients were acquired with a dual-detector SPECT/CT system and binned to eight ECG bins. First, activity ratio (AR)-the ratio of total activity in the last OSEM-reconstructed ECG bin and first five ECG bins-was computed, as well as standard deviation SD
resultsA strong negative correlation (r = -0.749) was found between SD
conclusionsTOSEM algorithm minimizes the HRV-related error and can be used to provide more robust phase analysis results.
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