ArticleScientific reports2019
Low vector competence in sylvatic mosquitoes limits Zika virus to initiate an enzootic cycle in South America.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Secondary vectors of Zika Virus, a systematic review of laboratory vector competence studies.PLoS neglected tropical diseases · 2023Pooled it
- Review
- Effect of landscape heterogeneity on mosquito abundance and sugar feeding behavior.Journal of medical entomology · 2026Article
- (Re)Emerging Arboviruses of Public Health Significance in the Brazilian Amazon.Microorganisms · 2025Review
- Detection of Zika Virus inViruses · 2023Article
- Biological and behavioral features and colonization of the sylvatic mosquito Sabethes identicus (Diptera: Culicidae).PloS one · 2023Article
- Multidisciplinary approach for surveillance and risk identification of yellow fever and other arboviruses in Colombia.One health (Amsterdam, Netherlands) · 2022Article
- Analysis of Zika Virus Sequence Data Associated with a School Cohort in Haiti.The American journal of tropical medicine and hygiene · 2022Article
- Lack of serological and molecular evidences of Zika virus circulation in non-human primates in three states from Brazil.Memorias do Instituto Oswaldo Cruz · 2022Article
- Review
- Microbial Composition in Larval Water Enhances Aedes aegypti Development but Reduces Transmissibility of Zika Virus.mSphere · 2021Article
- Natural Infection and Vertical Transmission of Zika Virus in Sylvatic MosquitoesTropical medicine and infectious disease · 2021Article
- No evidence for sylvatic cycles of chikungunya, dengue and Zika viruses in African green monkeys (Chlorocebus aethiops sabaeus) on St. Kitts, West Indies.Parasites & vectors · 2020Article
- High Speed Video Documentation of the Mosquito Sabethes albiprivus Egg-Catapulting Oviposition Behavior (Diptera: Culicidae).Neotropical entomology · 2020Article
- Into the woods: Changes in mosquito community composition and presence of key vectors at increasing distances from the urban edge in urban forest parks in Manaus, Brazil.Acta tropica · 2020Article
- From Anonymous to Public Enemy: How Does a Mosquito Become a Feared Arbovirus Vector?Pathogens (Basel, Switzerland) · 2020Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Zika virus (ZIKV) has spread in the Americas since 2015 and the potential establishment of a sylvatic transmission cycle in the continent has been hypothesized. We evaluated vector competence of five sylvatic Neotropical mosquito species to two ZIKV isolates. Distinct batches of Haemagogus leucoceleanus, Sabethes albiprivus, Sabethes identicus, Aedes terrens and Aedes scapularis females were respectively orally challenged and inoculated intrathoracically with ZIKV. Orally challenged mosquitoes were refractory or exhibited low infection rates. Viral dissemination was detected only in Hg. leucocelaenus, but with very low rates. Virus was not detected in saliva of any mosquito orally challenged with ZIKV, regardless of viral isolate and incubation time. When intrathoracically injected, ZIKV disseminated in high rates in Hg. leucocelaenus, Sa. identicus and Sa. albpiprivus, but low transmission was detected in these species; very low dissemination and no transmission was detected in Ae. terrens and Ae. scapularis. Together these results suggest that genetically determined tissue barriers, especially in the midgut, play a vital role in inhibiting ZIKV for transmission in the tested sylvatic mosquito species. Thus, an independent enzootic transmission cycle for ZIKV in South America is very unlikely.
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