ArticleScientific reports2019
The Effects of Previous Error and Success in Alzheimer's Disease and Mild Cognitive Impairment.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- The application of saccades to assess cognitive impairment among older adults: a systematic review and meta-analysis.Aging clinical and experimental research · 2023Pooled it
- Saccadic Eye Movement in Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review and Meta-Analysis.Neuropsychology review · 2022Pooled it
- Ocular changes as potential biomarkers for early diagnosis of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Eye movement abnormalities in Alzheimer's disease and other neurodegenerative dementias: insights from current evidence and priorities for future research.Frontiers in ophthalmology · 2025Review
- Late-life psychiatric factors and life satisfaction are associated with cognitive errors: evidence from an experimental module of a large-scale survey in India.Scientific reports · 2024Article
- The inhibitory effect of a recent distractor: singleton vs. multiple distractors.Experimental brain research · 2024Article
- A detection model of cognitive impairment via the integrated gait and eye movement analysis from a large Chinese community cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Research Progress of Eye Movement Analyses and its Detection Algorithms in Alzheimer's Disease.Current Alzheimer research · 2024Review
- Error monitoring in amnestic mild cognitive impairment: Cognitive correlates and relationship to measures of everyday function.Neuropsychology · 2023Article
- Random-Forest-Algorithm-Based Applications of the Basic Characteristics and Serum and Imaging Biomarkers to Diagnose Mild Cognitive Impairment.Current Alzheimer research · 2022Article
- The Potential of Naturalistic Eye Movement Tasks in the Diagnosis of Alzheimer's Disease: A Review.Brain sciences · 2021Review
- Digital reminiscence app co-created by people living with dementia and carers: Usability and eye gaze analysis.Health expectations : an international journal of public participation in health care and health policy · 2021Article
- The Disengagement of Visual Attention: An Eye-Tracking Study of Cognitive Impairment, Ethnicity and Age.Brain sciences · 2020Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work investigated in Alzheimer's disease dementia (AD), whether the probability of making an error on a task (or a correct response) was influenced by the outcome of the previous trials. We used the antisaccade task (AST) as a model task given the emerging consensus that it provides a promising sensitive and early biological test of cognitive impairment in AD. It can be employed equally well in healthy young and old adults, and in clinical populations. This study examined eye-movements in a sample of 202 participants (42 with dementia due to AD; 65 with mild cognitive impairment (MCI); 95 control participants). The findings revealed an overall increase in the frequency of AST errors in AD and MCI compared to the control group, as predicted. The errors on the current trial increased in proportion to the number of consecutive errors on the previous trials. Interestingly, the probability of errors was reduced on the trials that followed a previously corrected error, compared to the trials where the error remained uncorrected, revealing a level of adaptive control in participants with MCI or AD dementia. There was an earlier peak in the AST distribution of the saccadic reaction times for the inhibitory errors in comparison to the correct saccades. These findings revealed that the inhibitory errors of the past have a negative effect on the future performance of healthy adults as well as people with a neurodegenerative cognitive impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.