ArticleScientific reports2019
Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 42 citations in OpenAlex.
- Genomic diversification between aposematic and cryptic phenotypes of Oophaga granulifera (Anura: Dendrobatidae).Scientific reports · 2026Article
- Retinoic acid production via the ray-finned fish gene bco1l is essential for juvenile development.Genetics · 2026Article
- A Loss-of-Function Mutation inAnimals : an open access journal from MDPI · 2026Article
- Functional Analysis of theBiotech (Basel (Switzerland)) · 2026Article
- Effects of Dietary Vitamin A Concentration and Stress on Astaxanthin Utilization in Atlantic Salmon (Aquaculture nutrition · 2026Article
- Retinoic acid production via the ray-finned fish genebioRxiv : the preprint server for biology · 2025Article
- Surviving on Limited Resources: Effects of Caloric Restriction on Growth, Gene Expression and Gut Microbiota in a Species With Male Pregnancy (Hippocampus erectus).Molecular ecology · 2025Article
- Dietary Content of Plant Ingredients and Phospholipids Affects Astaxanthin Utilization and Lipid Deposition in Atlantic Salmon (Aquaculture nutrition · 2025Article
- Genome-wide association identifies genomic regions influencing fillet color in Northwest Atlantic salmon (Frontiers in genetics · 2024Article
- Effect of Dietary Cholesterol, Phytosterol, and Docosahexaenoic Acid on Astaxanthin Absorption and Retention in Rainbow Trout.Aquaculture nutrition · 2024Article
- RNA-Seq analysis of the pyloric caecum, liver, and muscle reveals molecular mechanisms regulating fillet color in rainbow trout.BMC genomics · 2023Article
- Multifaceted framework for defining conservation units: An example from Atlantic salmon (Evolutionary applications · 2023Article
- Dietary Level of the Omega-3 Fatty Acids EPA and DHA Influence the Flesh Pigmentation in Atlantic Salmon.Aquaculture nutrition · 2023Article
- Characteristics of a new carotenoid cleavage dioxygenase NtCCD10 derived from Nicotiana tabacum.Planta · 2022Article
- Article
- Genomic consequences of domestication of the Siamese fighting fish.Science advances · 2022Article
- Bench Research Informed by GWAS Results.Cells · 2021Review
- Molecular Mechanism Involved in Carotenoid Metabolism in Post-Smolt Atlantic Salmon: Astaxanthin Metabolism During Flesh Pigmentation and Its Antioxidant Properties.Marine biotechnology (New York, N.Y.) · 2021Article
- Genome-Wide Association Study RevealsFrontiers in genetics · 2021Article
- Genetic Parameters and Genome-Wide Association Studies of Quality Traits Characterised Using Imaging Technologies in Rainbow Trout,Frontiers in genetics · 2021Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Red coloration of muscle tissue (flesh) is a unique trait in several salmonid genera, including Atlantic salmon. The color results from dietary carotenoids deposited in the flesh, whereas the color intensity is affected both by diet and genetic components. Herein we report on a genome-wide association study (GWAS) to identify genetic variation underlying this trait. Two SNPs on ssa26 showed strong associations to the flesh color in salmon. Two genes known to be involved in carotenoid metabolism were located in this QTL- region: beta-carotene oxygenase 1 (bco1) and beta-carotene oxygenase 1 like (bco1l). To determine whether flesh color variation is caused by one, or both, of these genes, functional studies were carried out including mRNA and protein expression in fish with red and pale flesh color. The catalytic abilities of these two genes were also tested with different carotenoids. Our results suggest bco1l to be the most likely gene to explain the flesh color variation observed in this population.
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