Evidence map›Paper›PMID 31882709›Full record

ArticleScientific reports2019

The Prognostic Importance of CD20

Sofia Edin, Tuomas Kaprio, Jaana Hagström, Pär Larsson, Harri Mustonen, Camilla Böckelman, Karin Strigård, Ulf Gunnarsson, Caj Haglund, Richard Palmqvist

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 2 syntheses or guidelines pooled it, 142 citations in OpenAlex.

  1. Pooled it
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  19. Multimarker Assessment of B-Cell and Plasma Cell Subsets and Their Prognostic Role in the Colorectal Cancer Microenvironment.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  20. Review

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sofia EdinDepartment of Medical Biosciences/Pathology, Umeå University, Umeå, Sweden. sofia.edin@umu.se.
Tuomas KaprioDepartment of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Jaana HagströmTranslational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Pär LarssonDepartment of Medical Biosciences/Pathology, Umeå University, Umeå, Sweden.
Harri MustonenDepartment of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Camilla BöckelmanDepartment of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Karin StrigårdDepartment of Surgical and Perioperative Sciences/Surgery, Umeå University, Umeå, Sweden.
Ulf GunnarssonDepartment of Surgical and Perioperative Sciences/Surgery, Umeå University, Umeå, Sweden.
Caj HaglundDepartment of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Richard PalmqvistDepartment of Medical Biosciences/Pathology, Umeå University, Umeå, Sweden.
Umeå University · SEHelsinki University Hospital · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-tumour immune response is critical to patient prognosis in colorectal cancer (CRC). The aim of this study was to investigate infiltration of B lymphocytes into CRC tumours, and their clinical relevance, prognostic value and relation to other immune cell subsets. We used multiplexed immunohistochemistry and multispectral imaging to assay the amount of infiltrating CD20

Indexed as

AdultAgedAged, 80 and overAntigens, CD20BiomarkersB-LymphocytesColorectal NeoplasmsFemaleHumansLymphocytes, Tumor-InfiltratingLymphocyte SubsetsMaleMiddle AgedNeoplasm StagingPrognosisAntigens, CD20Biomarkers

Identifiers

PMID31882709
PMCPMC6934737
OpenAlexW2997011518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.