Evidence map›Paper›PMID 31882645›Full record

ArticleScientific reports2019

Evaluation of Selected Outcomes of Combination Antiretroviral Therapy: Yemen Cohort Retrospective Descriptive Studies.

Mayada Faisal Nabih, Sharifa Ezat Wan Puteh, Amrizal Muhammad Nur

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Mayada Faisal NabihNational AIDS Control Program - Ministry of Public Health and Population, Sana'a, Yemen. mayadanabih@yahoo.com.ORCID http://orcid.org/0000-0001-5067-7114
Sharifa Ezat Wan PutehCommunity Health Department - Faculty of Medicine Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia.
Amrizal Muhammad NurInternational Centre for Casemix and Clinical Coding (ITCC) - Faculty of Medicine Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia.
National University of Malaysia · MYSana'a University · YE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2007, HIV treatment services were established in five main governorates out of twenty-two which resulted in low access to services and poor treatment outcomes. The main goal of this study was to evaluate and analyse the selected treatment outcomes of eight cohorts of PLHIV who were treated with cART during 2007-2014. The method used was a retrospective descriptive study of 1,703 PLHIV who initiated cART at five public health facilities. The results: Retention rate was less than 80%, male: female ratio 1.661, with a mean age of 35 years (±9.2 SD), 85% had been infected with HIV via heterosexual contact. 65% of patients presented with clinical stages 3 and 4, and 52% of them were initiated cART at a CD4 T-cell count ≤200 cells/mm. 61% of cART included Tenofovir and Efavirenz. TB treatment started for 5% of PLHIV, and 22% developed HIV-related clinical manifestations after cART initiation. 67% of PLHIV had experienced cART substitution. The mean AIDS-mortality rate was 15% and the mean LTFU rate was 16%. Conclusion: Although cART showed effectiveness in public health, mobilization of resources and formulation of better health policies are important steps toward improving access to cART and achieving the desired treatment outcomes.

Indexed as

AdultAlkynesAnti-HIV AgentsAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveBenzoxazinesCD4 Lymphocyte CountCyclopropanesDrug Therapy, CombinationFemaleHIV InfectionsHumansMaleRetrospective StudiesTenofovirTreatment OutcomeAlkynesAnti-HIV AgentsAnti-Retroviral AgentsBenzoxazinesCyclopropanesefavirenzTenofovir

Identifiers

PMID31882645
PMCPMC6934668
OpenAlexW2998713713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.