Evidence map›Paper›PMID 31882608›Full record

ArticleScientific reports2019

Molecular Dynamics model of peptide-protein conjugation: case study of covalent complex between Sos1 peptide and N-terminal SH3 domain from Grb2.

Dmitrii A Luzik, Olga N Rogacheva, Sergei A Izmailov, Maria I Indeykina, Alexei S Kononikhin, Nikolai R Skrynnikov

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. BeyondChemical reviews · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Dmitrii A LuzikLaboratory of Biomolecular NMR, St. Petersburg State University, St. Petersburg, 199034, Russia.
Olga N RogachevaLaboratory of Biomolecular NMR, St. Petersburg State University, St. Petersburg, 199034, Russia.
Sergei A IzmailovLaboratory of Biomolecular NMR, St. Petersburg State University, St. Petersburg, 199034, Russia.
Maria I IndeykinaN.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119991, Russia.
Alexei S KononikhinN.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119991, Russia.
Nikolai R SkrynnikovLaboratory of Biomolecular NMR, St. Petersburg State University, St. Petersburg, 199034, Russia. nikolai@purdue.edu.
Institute of Biochemical Physics NM Emanuel · RUSt Petersburg University · RUInstitute of Experimental Medicine · RUPurdue University West Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have investigated covalent conjugation of VPPPVPPRRRX' peptide (where X' denotes N

Indexed as

Molecular Dynamics Simulationsrc Homology DomainsAlgorithmsAmino Acid SequenceAnimalsElectrophoresis, Polyacrylamide GelGRB2 Adaptor ProteinHumansMagnetic Resonance SpectroscopyMicePeptide FragmentsPeptidesProtein BindingProtein ConformationSOS1 ProteinTandem Mass SpectrometryGRB2 Adaptor ProteinGRB2 protein, humanPeptide FragmentsPeptidesSOS1 Protein

Identifiers

PMID31882608
PMCPMC6934455
OpenAlexW2997838821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.