Evidence map›Paper›PMID 31882466›Full record

ArticleIn vivo (Athens, Greece)

Radical-scavenging and Pro-/anti-inflammatory Activity of Tetracycline and Related Phenolic Compounds With or Without Visible Light Irradiation.

Yukio Murakami, Akifumi Kawata, Seiji Suzuki, Seiichiro Fujisawa

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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    Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yukio MurakamiDivision of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Japan ymura@dent.meikai.ac.jp.
Akifumi KawataDivision of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Japan.
Seiji SuzukiDivision of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Japan.
Seiichiro FujisawaDivision of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Japan.
Meikai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimMicrobial tetracycline (TC) pastes have been employed to treat oral bacterial infection. In the present study, we investigated the kinetic radical-scavenging and pro-/anti-inflammatory activity of TC with or without visible light irradiation (VLI). MATERIALS AND

methodsThe radical-scavenging activity of TC and minocycline (MC) was determined by differential scanning calorimetry (DSC). The stoichiometric factor (n) and the rate constant of inhibition and propagation (k

resultsThe n and k

conclusionTC is a chain-breaking antioxidant with a large k

Indexed as

AnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsCell LineCyclooxygenase 2Cyclooxygenase 2 InhibitorsDown-RegulationFree Radical ScavengersHeme Oxygenase-1LipopolysaccharidesMacrophagesMiceNitric Oxide Synthase Type IIPeriodontal DiseasesPhenolsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsCyclooxygenase 2Cyclooxygenase 2 InhibitorsFree Radical ScavengersHeme Oxygenase-1LipopolysaccharidesNitric Oxide Synthase Type IIPhenolsQuercetinResveratrolRNA, MessengerTetracyclinesTumor Necrosis Factor-alphaCox2Ho-1LPSNos2Radical-scavenging activityRAW264.7 celltetracyclinesTnfαvisible light

Identifiers

PMID31882466
PMCPMC6984092
OpenAlexW2996887116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.