ReviewIn vivo (Athens, Greece)
Intraoperative Indocyanine Green (ICG) Angiography for the Identification of the Parathyroid Glands: Current Evidence and Future Perspectives.
Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Near-infrared (NIR) Fluorescence Imaging With Indocyanine Green (ICG) for Identification of Sentinel Lymph Nodes and Parathyroid Glands During Total Thyroidectomy: Prospective Randomized Clinical Trial
The Use of Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Total Thyroidectomy: A Randomized Clinical Trial
Analysis of Parathyroid Vascularization During Total Thyroidectomy Using Quantitative Real-time Indocyanine Green Angiography
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Indocyanine green (ICG) guided thyroidectomy versus conventional thyroidectomy and the impact on parathyroid function preservation: an updated GRADE-assessed systematic review and meta-analysis.Langenbeck's archives of surgery · 2026Pooled it
- Comparing ICG-Guided vs. Conventional Laparoscopic Lymphadenectomy in Gastric Cancer: A Systematic Review and Meta-Analysis.Journal of gastrointestinal cancer · 2025Pooled it
- Efficacy and safety of parathyroid perfusion assessment by fine-needle prick during thyroid surgery: a prospective study.Frontiers in endocrinology · 2025Trial
- Quantitative optimisation of indocyanine green fluorescence for parathyroid imaging in robotic BABA thyroidectomy: a prospective cohort study.Surgical endoscopy · 2026Article
- Vascularity Assessment of Parathyroid Glands Using Low-Dose ICG and Probe-Based Fluorescence Detection.Annals of surgical oncology · 2026Article
- Calculation of postoperative parathyroid hormone level using indocyanine green angiography during robotic total thyroidectomy: equivalent function hypothesis.Surgical endoscopy · 2026Article
- Response to letter regarding: [Letter to the editor: impact of parathyroid gland classification on hypoparathyroidism following total thyroidectomy with central neck dissection for differentiated thyroid cancer].Annals of medicine · 2025Article
- Incident Dark-Field (IDF) Illumination Microscopy as a Novel Tool for Real-Time, Dye-Free Parathyroid Perfusion Assessment in Thyroid Surgery.Annals of surgical oncology · 2025Article
- Parathyroid glands viability assessment and identification during surgery with multimodal diffuse reflectance spectroscopy and NIR autofluorescence probe.Scientific reports · 2025Article
- Molecular Gold Nanoclusters for Advanced NIR-II Bioimaging and Therapy.Chemical reviews · 2025Review
- The research progress of label-free optical imaging technology in intraoperative real-time navigation of parathyroid glands.Lasers in medical science · 2025Review
- Meta-Analysis of Image-Based Versus Probe-Based Parathyroid Near-Infrared Autofluorescence.Cureus · 2025Review
- Parathyroid gland identification and angiography classification using simple machine learning methods.BJS open · 2024Article
- Article
- Silicon-Rhodamine Functionalized Evocalcet Probes Potently and Selectively Label Calcium Sensing ReceptorsACS pharmacology & translational science · 2024Article
- Article
- Intraoperative indocyanine green angiography for predicting postoperative hypoparathyroidism.Surgical endoscopy · 2023Article
- Pre-incisional, trans-isthmic injection of indocyanine green for lymph node mapping during the transoral endoscopic thyroidectomy vestibular approach.Updates in surgery · 2023Article
- Recent Advances in the Surgical Management of Thyroid Cancer.Current oncology (Toronto, Ont.) · 2023Review
- Fluorescence-guided surgery: comprehensive review.BJS open · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimRecently, indocyanine green (ICG) fluorescence imaging has been used for the identification of the parathyroid glands (PG) during thyroid and parathyroid surgery. However, an overall consensus on the optimal technique, the dosage, the timing of the ICG administration and finally its interpretation and clinical usefulness is still lacking evidence. The aim of this review is to investigate the use of ICG angiography during thyroidectomy and/or parathyroidectomy for identification as well as for the perfusion integrity of the parathyroid glands. MATERIALS AND
methodsThe PubMed database was systematically searched for publications regarding intraoperative ICG imaging in patients that undergo thyroidectomy or parathyroidectomy.
resultsEighteen publications reporting on 612 patients, namely 71 parathyroidectomy and 541 thyroidectomy patients met the inclusion criteria. Eleven publications reported the use of ICG angiography for the identification of the parathyroid glands during thyroidectomy and seven during parathyroidectomy for primary and secondary hyperparathyroidism.
conclusionICG fluorescence imaging is a simple, fast and reproducible method capable of intraoperatively visualizing and assessing the function of parathyroid glands, and can, therefore, assist surgeons in their decision-making. Despite all this, ICG fluorescence imaging technique for PG detection still lacks standardization and further studies are needed to establish its clinical utility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.