Evidence map›Paper›PMID 31882446›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation.

Badri N Dubey, Elia Agustoni, Raphael Böhm, Andreas Kaczmarczyk, Francesca Mangia, Christoph von Arx, Urs Jenal, Sebastian Hiller, Iván Plaza-Menacho, Tilman Schirmer

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. An Unusual Component of the Multistep Phosphorelay from Tea Plant (International journal of molecular sciences · 2026
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  10. A Model of the Full-Length Cytokinin Receptor: New Insights and Prospects.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Badri N DubeyStructural Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.ORCID 0000-0002-8626-8918
Elia AgustoniStructural Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.ORCID 0000-0003-4003-7580
Raphael BöhmStructural Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.ORCID 0000-0003-2545-997X
Andreas KaczmarczykInfection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.ORCID 0000-0002-6616-1777
Francesca MangiaStructural Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.
Christoph von ArxInfection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.
Urs JenalInfection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.
Sebastian HillerStructural Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.ORCID 0000-0002-6709-4684
Iván Plaza-MenachoStructural Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland.
Tilman SchirmerStructural Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland; tilman.schirmer@unibas.ch.ORCID 0000-0001-9512-8346
University of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytosolic hybrid histidine kinases (HHKs) constitute major signaling nodes that control various biological processes, but their input signals and how these are processed are largely unknown. In

Indexed as

Bacterial ProteinsCaulobacter crescentusCell CycleCrystallography, X-RayCyclic GMPHistidine KinaseModels, MolecularMolecular Dynamics SimulationPhosphorylationProtein BindingProtein ConformationProtein DomainsSecond Messenger SystemsBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPHistidine Kinaseautophosphorylationc-di-GMPhybrid histidine kinase

Identifiers

PMID31882446
PMCPMC6969517
OpenAlexW2996935324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.