Evidence map›Paper›PMID 31882403›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Midkine-a Is Required for Cell Cycle Progression of Müller Glia during Neuronal Regeneration in the Vertebrate Retina.

Mikiko Nagashima, Travis S D'Cruz, Antoinette E Danku, Doneen Hesse, Christopher Sifuentes, Pamela A Raymond, Peter F Hitchcock

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
  6. Article
  7. Review
  8. Monocyte Invasion into the Retina Restricts the Regeneration of Neurons from Müller Glia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Brain sciences · 2022
    Article
  19. Article
  20. Plasticity of cell proliferation in the retina ofCurrent research in neurobiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mikiko NagashimaDepartment of Ophthalmology and Visual Sciences, and.
Travis S D'CruzDepartment of Ophthalmology and Visual Sciences, and.
Antoinette E DankuDepartment of Ophthalmology and Visual Sciences, and.
Doneen HesseDepartment of Ophthalmology and Visual Sciences, and.
Christopher SifuentesDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48105.
Pamela A RaymondDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48105.
Peter F HitchcockDepartment of Ophthalmology and Visual Sciences, and peterh@umich.edu.ORCID 0000-0001-9454-2684
University of Michigan · US

Funding

VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Antonetti · 1987 to 2026
$17.6M
RETINAL DEVELOPMENT--DENDRITIC GROWTH SYNAPSER01EY007060 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HITCHCOCK, PETER F · 1987 to 2021
$7.0M
NEI NIH HHS P30 EY007003NEI NIH HHS R01 EY007060
6 · The paper itself

Abstract

In the retina of zebrafish, Müller glia have the ability to reprogram into stem cells capable of regenerating all classes of retinal neurons and restoring visual function. Understanding the cellular and molecular mechanisms controlling the stem cell properties of Müller glia in zebrafish may provide cues to unlock the regenerative potential in the mammalian nervous system. Midkine is a cytokine/growth factor with multiple roles in neural development, tissue repair, and disease. In

Indexed as

NeurogliaRetinaAnimalsAnimals, Genetically ModifiedCell CycleCell DedifferentiationCell ProliferationCellular ReprogrammingMidkineNerve RegenerationNeural Stem CellsZebrafishZebrafish ProteinsMidkineZebrafish Proteinsneurogenesisphotoreceptorsproliferationreprogrammingzebrafish

Identifiers

PMID31882403
PMCPMC7002140
OpenAlexW2998190119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.