Evidence map›Paper›PMID 31882402›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

ICAM5 as a Novel Target for Treating Cognitive Impairment in Fragile X Syndrome.

Ya-Ping Pei, Yue-Yi Wang, Dan Liu, Hui-Yang Lei, Zhi-Hao Yang, Zi-Wei Zhang, Man Han, Ke Cheng, Yu-Shan Chen, Jin-Quan Li and 7 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 3 countries.

Ya-Ping PeiBrain Science and Advanced Technology Institute.
Yue-Yi WangBrain Science and Advanced Technology Institute.
Dan LiuBrain Science and Advanced Technology Institute.
Hui-Yang LeiDepartment of Pathophysiology, School of Basic Medicine and The Collaborative Innovation Center for Brain Science, Key Laboratory of Hubei Province and Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China, and.
Zhi-Hao YangBrain Science and Advanced Technology Institute.
Zi-Wei ZhangBrain Science and Advanced Technology Institute.
Man HanBrain Science and Advanced Technology Institute.
Ke ChengBrain Science and Advanced Technology Institute.
Yu-Shan ChenBrain Science and Advanced Technology Institute.
Jin-Quan LiBrain Science and Advanced Technology Institute.
Gui-Rong ChengBrain Science and Advanced Technology Institute.
Lang XuBrain Science and Advanced Technology Institute.
Qing-Ming WuBrain Science and Advanced Technology Institute.
Shawn M McClintockBrain Science and Advanced Technology Institute.
Ying YangDepartment of Pathophysiology, School of Basic Medicine and The Collaborative Innovation Center for Brain Science, Key Laboratory of Hubei Province and Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China, and.
Yong ZhangDepartment of Neurobiology, School of Basic Medical Sciences and Neuroscience Research Institute, and Key Laboratory for Neuroscience, Ministry of Education of China and National Committee of Health and Family Planning of China, Peking University, Beijing 100191, People's Republic of China.
Yan ZengBrain Science and Advanced Technology Institute, yanzeng11@foxmail.com.
Wuhan University of Science and Technology · CNHuazhong University of Science and Technology · CNMinistry of Education · MESouthwestern Medical Center

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability, resulted from the silencing of the

Indexed as

AnimalsCognitive DysfunctionDendritic SpinesFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeGene Expression RegulationMaleMembrane GlycoproteinsMiceMice, KnockoutNerve Tissue ProteinsNeurogenesisFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1Icam5 protein, mouseMembrane GlycoproteinsNerve Tissue Proteinscognitive impairmentdendritic spine maturationFMRP/ICAM5 mRNA interactionfragile X mental retardation proteinfragile X syndromeintercellular adhesion molecule 5

Identifiers

PMID31882402
PMCPMC7002157
OpenAlexW2997997598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.