Observational studyBMC anesthesiology2019
Evaluation of peripheral perfusion index and heart rate variability as early predictors for intradialytic hypotension in critically ill patients.
Observational study in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Prevalence of cardiovascular instability during hemodialysis therapy in hospitalized patients: A systematic review and meta-analysis.Science progressPooled it
- Article
- Could Perfusion and Pleth Variability Index Be Useful in Managing Treatment and Morbidity in Patients with Gastrointestinal Bleeding?Journal of clinical medicine · 2026Article
- The value of pleth variability index in predicting hypotension during maintenance hemodialysis: a prospective observational multicenter study (PVi-HD study).BMC nephrology · 2026Observational
- Ultrafiltration in the critically ill patient: a framework for personalized care.Critical care (London, England) · 2026Review
- Identifying a high-risk CKM syndrome phenotype: association of albuminuria with subclinical hemodynamic alterations via portable noninvasive cardiometer.Frontiers in endocrinology · 2026Article
- Optimizing the timing of painless gastroscope insertion: integrating advanced monitoring tools to enhance safety and efficacy: a narrative review.Frontiers in medicine · 2026Review
- Evaluation of intradialytic hypoxemia development in intensive care patients.BMC nephrology · 2025Observational
- Feasibility study of using perfusion index to predict the timing of laryngeal mask insertion: an observational study.BMC anesthesiology · 2025Observational
- Ultrafiltration Tolerance and Improving Outcomes with Continuous Renal Replacement Therapies.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Predictors of intradialytic hypotension in critically ill patients undergoing kidney replacement therapy: a systematic review.Intensive care medicine experimental · 2024Review
- Early peripheral perfusion monitoring in septic shock.European journal of medical research · 2024Review
- Peripheral perfusion index of pulse oximetry in adult patients: a narrative review.European journal of medical research · 2024Review
- Association of the perfusion index with postoperative acute kidney injury: a retrospective study.Korean journal of anesthesiology · 2023Article
- Plethysmographic Peripheral Perfusion Index: Could It Be a New Vital Sign?Frontiers in medicine · 2021Review
- To Study the Role of Perfusion Index as a Predictor of Hypotension during Spinal Anesthesia in Lower Segment Cesarean Section - A Prospective Observational Study.Anesthesia, essays and researchesArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntradialytic hypotension is a serious complication during renal replacement therapy in critically ill patients. Early prediction of intradialytic hypotension could allow adequate prophylactic measures. In this study we evaluated the ability of peripheral perfusion index (PPI) and heart rate variability (HRV) to predict intradialytic hypotension.
methodsA prospective observational study included 36 critically ill patients with acute kidney injury during their first session of intermittent hemodialysis. In addition to basic vital signs, PPI was measured using Radical-7 (Masimo) device. Electrical cardiometry (ICON) device was used for measuring cardiac output, systemic vascular resistance, and HRV. All hemodynamic values were recorded at the following time points: 30 min before the hemodialysis session, 15 min before the start of hemodialysis session, every 5 min during the session, and 15 min after the conclusion of the session. The ability of all variables to predict intradialytic hypotension was assessed through area under receiver operating characteristic (AUROC) curve calculation.
resultsTwenty-three patients (64%) had intradialytic hypotension. Patients with pulmonary oedema showed higher risk for development of intradialytic hypotension {Odds ratio (95% CI): 13.75(1.4-136)}. Each of baseline HRV, and baseline PPI showed good predictive properties for intradialytic hypotension {AUROC (95% CI): 0.761(0.59-0.88)}, and 0.721(0.547-0.857)} respectively.
conclusionsEach of low PPI, low HRV, and the presence of pulmonary oedema are good predictors of intradialytic hypotension.
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