Evidence map›Paper›PMID 31881916›Full record

ArticleTrials2019

The BrainACT study: acceptance and commitment therapy for depressive and anxiety symptoms following acquired brain injury: study protocol for a randomized controlled trial.

Johanne Rauwenhoff, Frenk Peeters, Yvonne Bol, Caroline Van Heugten

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Johanne RauwenhoffSchool for Mental Health and Neuroscience, Department of Psychiatry and Psychology, Maastricht University Medical Centre, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-0064-6560
Frenk PeetersDepartment of Clinical Psychological Science, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Yvonne BolDepartment of Clinical and Medical Psychology, Zuyderland Medical Centre, P.O. Box 5500, 6130 MB, Sittard, The Netherlands.
Caroline Van HeugtenSchool for Mental Health and Neuroscience, Department of Psychiatry and Psychology, Maastricht University Medical Centre, P.O. Box 616, 6200 MD, Maastricht, The Netherlands. caroline.vanheugten@maastrichtuniversity.nl.
Maastricht University Medical Centre · NLMaastricht University · NLZuyderland Medisch Centrum · NL

Funding

ZonMW 63631 0003
6 · The paper itself

Abstract

backgroundFollowing an acquired brain injury, individuals frequently experience anxiety and/or depressive symptoms. However, current treatments for these symptoms are not very effective. A promising treatment is acceptance and commitment therapy (ACT), which is a third-wave behavioural therapy. The primary goal of this therapy is not to reduce symptoms, but to improve psychological flexibility and general well-being, which may be accompanied by a reduction in symptom severity. The aim of this study is to investigate the effectiveness of an adapted ACT intervention (BrainACT) in people with acquired brain injury who experience anxiety and/or depressive symptoms.

methodsThe study is a multicenter, randomized, controlled, two-arm parallel trial. In total, 94 patients who survive a stroke or traumatic brain injury will be randomized into an ACT or control (i.e. psycho-education and relaxation) intervention. The primary outcome measures are the Hospital Anxiety and Depression Scale and the Depression Anxiety Stress Scale. Outcomes will be assessed by trained assessors, blinded to treatment condition, pre-treatment, during treatment, post-treatment, and at 7 and 12 months. DISCUSSION: This study will contribute to the existing knowledge on how to treat psychological distress following acquired brain injury. If effective, BrainACT could be implemented in clinical practice and potentially help a large number of patients with acquired brain injury.

trial registrationDutch Trial Register, NL691, NTR 7111. Registered on 26 March 2018. https://www.trialregister.nl/trial/6916.

Indexed as

AnxietyBrain InjuriesDepressionAcceptance and Commitment TherapyAdultHumansMulticenter Studies as TopicPsychiatric Status Rating ScalesPsychological DistressRandomized Controlled Trials as TopicResearch DesignTreatment OutcomeAcceptance and commitment therapyAcquired brain injuryAnxietyDepressionProtocolRCT

Identifiers

PMID31881916
PMCPMC6935100
OpenAlexW2996941602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.