ArticleMalaria journal2019
Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda.
Article in Malaria journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Integrated malaria prevention in low- and middle-income countries: a systematic review.Malaria journal · 2023Pooled it
- Permethrin-Treated Baby Wraps for the Prevention of Malaria.The New England journal of medicine · 2025Trial
- Trial
- Entomological indicators of malaria transmission prior to a cluster-randomized controlled trial of a 'lethal house lure' intervention in central Côte d'Ivoire.Malaria journal · 2022Trial
- Permethrin-treated baby wraps for the prevention of malaria: results of a randomized controlled pilot study in rural Uganda.Malaria journal · 2022Trial
- Malaria Prevalence Near African Mangroves: Negative Association With Mangrove Extent, but Positive Association With Mangrove Greenness.Global change biology · 2026Article
- Integrating routinely collected mosquito vector and human behavioral data for malaria prevention: A case example in central region Malawi.Malaria journal · 2026Article
- Anopheles gambiae biting behavior and malaria transmission risk in Simiw, a community located in the coastal forest zone of the Central Region of Ghana.Malaria journal · 2026Article
- Impact of indoor residual spraying and insecticide-treated nets on malaria burden in 8 districts in West Nile and Acholi regions, Uganda: a quasi-experimental study.BMC global and public health · 2026Article
- Hotspot Mapping, Spatiotemporal Clustering and Forecasting of Malaria Incidence in Uganda, 2014-2023: Strategies to Inform Targeted Public Health Interventions.Journal of epidemiology and global health · 2026Article
- Fatal and non-fatal health outcomes of malaria among reproductive age women in Eastern Sub-Saharan Africa, from 1990 to 2023.Malaria journal · 2026Article
- The genomics of insecticide resistance in Anopheles funestus: insights from a large bed-net trial.BMC genomics · 2026Article
- Malaria: a review on its current epidemiological status and management strategies.Malaria journal · 2026Review
- Beyond Anopheles gambiae sensu lato: exploring the impact of non-dominant Anopheles species on malaria persistence in high-transmission endemic areas of Burkina Faso.Parasites & vectors · 2026Article
- Chlorfenapyr bednets effectively overcome pyrethroid resistance escalation in highly resistant Anopheles malaria vectors in Uganda.Scientific reports · 2026Article
- Modelling the impact of mosquito bed net utilization on malaria transmission and evolution of pyrethroid resistance.PloS one · 2026Article
- Effectiveness of the Smart Home Model for Integrated Malaria Prevention: A Case-Control Study in Oyam District, Uganda.Journal of tropical medicine · 2026Article
- Article
- Insecticide-treated net use and elimination of malaria in Sub-Saharan African countries: assessing the Global Technical Strategy using an evolutionary game approach.BMC infectious diseases · 2025Article
- Mapping the Genetic Relatedness of Outdoor-BitingInsects · 2025Article
22 more citing papers are in PubMed but not listed here.
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Abstract
backgroundLong-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) are widely recommended for the prevention of malaria in endemic regions. Data from human landing catches provide information on the impact of vector control on vector populations. Here, malaria transmission indoors and outdoors, before and after mass deployment of LLINs and IRS in Uganda was compared.
methodsThe study took place in Tororo district, a historically high transmission area where universal LLIN distribution was conducted in November 2013 and May 2017 and 6 rounds of IRS implemented from December 2014 to July 2018. Human landing catches were performed in 8 houses monthly from October 2011 to September 2012 (pre-intervention period) and every 4 weeks from November 2017 to October 2018 (post-intervention period). Mosquitoes were collected outdoors from 18:00 to 22:00 h and indoors from 18:00 to 06:00 h. Female Anopheles were tested for the presence of Plasmodium falciparum sporozoites and species identification performed using gross dissection and polymerase chain reaction (PCR).
resultsThe interventions were associated with a decline in human biting rate from 19.6 to 2.3 female Anopheles mosquitoes per house per night (p < 0.001) and annual entomological inoculation rate from 129 to 0 infective bites per person per year (p < 0.001). The proportion of mosquitoes collected outdoors increased from 11.6 to 49.4% (p < 0.001). Prior to the interventions the predominant species was Anopheles gambiae sensu stricto (s.s.), which comprised an estimated 76.7% of mosquitoes. Following the interventions, the predominant species was Anopheles arabiensis, which comprised 99.5% of mosquitoes, with almost complete elimination of An. gambiae s.s. (0.5%).
conclusionsMass distribution of LLINs and 6 rounds of IRS dramatically decreased vector density and sporozoite rate resulting in a marked reduction in malaria transmission intensity in a historically high transmission site in Uganda. These changes were accompanied by a shift in vector species from An. gambiae s.s. to An. arabiensis and a relative increase in outdoor biting.
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