ReviewInternational journal of molecular sciences2019
Association of Elite Sports Status with Gene Variants of Peroxisome Proliferator Activated Receptors and Their Transcriptional Coactivator.
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Socceromics: A Systematic Review of Omics Technologies to Optimize Performance and Health in Soccer.International journal of molecular sciences · 2026Pooled it
- Effect Size and Replicability in Genetic Studies of Athletic Performance: A Meta-Analytical Review.Genes · 2025Pooled it
- Pooled it
- Nutrigenetic Markers Related to Nutrient Metabolism, Recovery, and Performance in Athletes: a Review of Current Evidence.Current nutrition reports · 2026Review
- Genes and Injuries in Sports: A Systematic Review and Meta-Analysis.Journal of human kinetics · 2026Review
- Precision Medicine in Astronauts: Principles and Targets in Molecular Assessment.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Genetic Susceptibility to Sport-Related Muscle Injuries: Insights from the Literature and Novel Gene Candidates.International journal of molecular sciences · 2025Review
- Polymorphisms of PPARα and ACTN3 Among Adolescent Egyptian Athletes: A Case-Control Study.Life (Basel, Switzerland) · 2025Article
- Review
- Importance of selected genetic determinants on endurance performance and physical strength: a narrative review.Frontiers in physiology · 2025Review
- Role of theGenes · 2024Review
- Impact of theJournal of human kinetics · 2024Article
- PPARs in Clinical Experimental Medicine after 35 Years of Worldwide Scientific Investigations and Medical Experiments.Biomolecules · 2024Review
- Common protein-coding variants influence the racing phenotype in galloping racehorse breeds.Communications biology · 2022Article
- Speed and power-related gene polymorphisms associated with playing position in elite soccer players.Biology of sport · 2022Article
- PGC-1α protects from myocardial ischaemia-reperfusion injury by regulating mitonuclear communication.Journal of cellular and molecular medicine · 2022Review
- Genetic profiles to identify talents in elite endurance athletes and professional football players.PloS one · 2022Article
- Review
- Genetic basis of elite combat sports athletes: a systematic review.Biology of sport · 2021Article
- Total Genotype Score Modelling of Polygenic Endurance-Power Profiles in Lithuanian Elite Athletes.Genes · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundAlthough the scientific literature regarding sports genomics has grown during the last decade, some genes, such as peroxisome proliferator activated receptors (PPARs), have not been fully described in terms of their role in achieving extraordinary sports performance. Therefore, the purpose of this systematic review was to determine which elite sports performance constraints are positively influenced by PPARs and their coactivators.
methodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were used, with a combination of PPAR and sports keywords.
resultsIn total, 27 studies that referred to PPARs in elite athletes were included, where the Ala allele in
conclusionsPPARs can be used for estimating the potential to achieve elite status in human physical performance in strength and power, team, and aerobic sports disciplines. Carrying specific PPAR alleles can provide a partial benefit to achieving elite sports status, but does not preclude achieving elite status if they are absent.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.