Evidence map›Paper›PMID 31881666›Full record

ArticleMolecules (Basel, Switzerland)2019

Association of mRNA Levels of IL6, MMP-8, GSS in Saliva and Pyelonephritis in Children.

Sirma Angelova, Ayshe Salim, Yoana Kiselova-Kaneva, Diana Ivanova, Stefan Peev

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. An Exploratory Study Demonstrating That Salivary Cytokine Profiles Are Altered in Children With Small Area Thermal Injury.Journal of burn care & research : official publication of the American Burn Association · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sirma AngelovaDepartment of Pediatric Dentistry, Faculty of Dental Medicine, Medical University of Varna, 9000 Varna, Bulgaria.
Ayshe SalimDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, 9000 Varna, Bulgaria.ORCID 0000-0002-1422-7121
Yoana Kiselova-KanevaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, 9000 Varna, Bulgaria.
Diana IvanovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, 9000 Varna, Bulgaria.
Stefan PeevDepartment of Periodontology and Dental Implantology, Faculty of Dental Medicine, Medical University of Varna, 9000 Varna, Bulgaria.
Medical University of Varna · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, saliva is a subject of growing scientific interest because of its definite advantages as diagnostic medium. The aim of our study was to investigate the diagnostic potential and reliability of messenger RNAs (mRNAs) of selected genes-interleukin-6 (IL-6), matrix metalloproteinase-8 (MMP-8) and glutathione synthetase (GSS)-as salivary markers in children with diagnosed pyelonephritis and to correlate their levels with typical urine para-clinical indicators of the disease. Analysis of the mRNA levels for IL-6, MMP-8 and GSS in 28 children hospitalized with the diagnosis of pyelonephritis was conducted applying the method of quantitative reverse transcription polymerase chain reaction (RT-qPCR). In the study group (

Indexed as

BiomarkersChildChild, PreschoolFemaleGlutathione SynthaseHumansInterleukin-6MaleMatrix Metalloproteinase 8PyelonephritisRNA, MessengerSalivaBiomarkersGlutathione SynthaseInterleukin-6Matrix Metalloproteinase 8RNA, MessengerchildrencorrelationGSSMMP-8mRNA levelspyelonephritissalivary biomarkers of IL-6

Identifiers

PMID31881666
PMCPMC6982834
OpenAlexW2998226062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.