Evidence map›Paper›PMID 31881643›Full record

ArticleCancers2019

Noemi García-Romero, Josefa Carrión-Navarro, Pilar Areal-Hidalgo, Ana Ortiz de Mendivil, Adriá Asensi-Puig, Rodrigo Madurga, Rocio Núñez-Torres, Anna González-Neira, Cristobal Belda-Iniesta, Victor González-Rumayor and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Cell-free DNA-based liquid biopsies in neurology.Brain : a journal of neurology · 2023
    Review
  11. Article
  12. Review
  13. Liquid biopsy: early and accurate diagnosis of brain tumor.Journal of cancer research and clinical oncology · 2022
    Review
  14. Circulating tumor DNA profiling for childhood brain tumors: Technical challenges and evidence for utility.Laboratory investigation; a journal of technical methods and pathology · 2022
    Review
  15. Circulating Tumor DNA in Pediatric Cancer.Frontiers in molecular biosciences · 2022
    Review
  16. Article
  17. Review
  18. Article
  19. Liquid Biomarkers for Improved Diagnosis and Classification of CNS Tumors.International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Noemi García-RomeroFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.ORCID 0000-0001-7744-8848
Josefa Carrión-NavarroFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.
Pilar Areal-HidalgoFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.
Ana Ortiz de MendivilFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.
Adriá Asensi-PuigAtrys Health, 08025 Barcelona, Spain.ORCID 0000-0002-2764-4768
Rodrigo MadurgaFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.ORCID 0000-0002-1381-2599
Rocio Núñez-TorresSpanish National Cancer Research Center (CNIO), 28029 Madrid, Spain.
Anna González-NeiraSpanish National Cancer Research Center (CNIO), 28029 Madrid, Spain.
Cristobal Belda-IniestaFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.
Victor González-RumayorAtrys Health, 08025 Barcelona, Spain.
Blanca López-IborFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.ORCID 0000-0002-6419-6773
Angel Ayuso-SacidoFundación de Investigación HM Hospitales, HM Hospitales, 28015 Madrid, Spain.
HM Hospitales · ESEcorys (Netherlands) · NLSpanish National Cancer Research Centre · ESUniversidad San Pablo CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric Central Nervous System (CNS) tumors are the most fatal cancer diseases in childhood. Due to their localization and infiltrative nature, some tumor resections or biopsies are not feasible. In those cases, the use of minimally invasive methods as diagnostic, molecular marker detection, prognostic or monitoring therapies are emerging. The analysis of liquid biopsies which contain genetic information from the tumor has been much more widely explored in adults than in children. We compare the detection of

Indexed as

BRAFdabrafenibliquid biopsypediatric brain tumors

Identifiers

PMID31881643
PMCPMC7016762
OpenAlexW2998182956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.