Evidence map›Paper›PMID 31881390›Full record

ArticleContemporary clinical trials2020

Patient randomized trial of a targeted navigation program to improve rates of follow-up colonoscopy in community health centers.

Gloria D Coronado, Eric S Johnson, Michael C Leo, Jennifer L Schneider, David Smith, Raj Mummadi, Amanda F Petrik, Jamie H Thompson, Ricardo Jimenez

Registry-linked trialOpen access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03925883 (Predicting and Addressing Colonoscopy in Safety Net Settings), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03925883 nacompletednot on this map

Predicting and Addressing Colonoscopy in Safety Net Settings

TypeinterventionalSponsorKaiser PermanenteRan2019 to 2023Enrolled1,200ConditionsColorectal CancerArmsPatient navigation
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Randomized in error in pragmatic clinical trials.Contemporary clinical trials · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Data Challenges in Identifying Patients Due for Colorectal Cancer Screening in Rural Clinics.Journal of the American Board of Family Medicine : JABFM · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Gloria D CoronadoCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA. Electronic address: Gloria.D.Coronado@kpchr.org.
Eric S JohnsonCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Michael C LeoCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Jennifer L SchneiderCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
David SmithCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Raj MummadiNorthwest Permanente Medical Group, Portland, OR, USA.
Amanda F PetrikCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Jamie H ThompsonCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Ricardo JimenezSea Mar Community Health Centers, Seattle, WA, USA.
Kaiser Permanente Center for Health Research · USColorado Permanente Medical Group · USCommunity Health Center · US

Funding

Prediciting and addressing colonoscopy non-adherence in community settingsR01CA218923 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORONADO, GLORIA D · 2018 to 2022
$3.5M
NCI NIH HHS R01 CA218923
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) screening by annual fecal immunochemical test (FIT) is an accessible and cost-effective strategy to lower CRC incidence and mortality. However, this mode of screening depends on follow-up colonoscopy after a positive FIT result. Unfortunately, nearly one-half of FIT-positive patients fail to complete this essential screening component. Patient navigation may improve follow-up colonoscopy adherence. To deliver patient navigation cost-effectively, health centers could target navigation to patients who are unlikely to complete the procedure on their own.

objectivesThe Predicting and Addressing Colonoscopy Non-adherence in Community Settings (PRECISE) clinical trial will validate a risk model of follow-up colonoscopy adherence and test whether patient navigation raises rates of colonoscopy adherence overall and among patients in each probability stratum (low, moderate, and high probability of adherence without intervention).

methodsPRECISE is a collaboration with a large community health center whose patient population is 37% Latino. Eligible patients will be aged 50-75, have an abnormal FIT result in the past month, and be due for a follow-up colonoscopy. Patients will be randomized to patient navigation or usual care. Primary outcomes will be colonoscopy completion within one year of a positive FIT result, cost, and cost-effectiveness. Secondary outcomes will include time to colonoscopy receipt, adequacy of bowel prep, and communication of results to primary care providers. Primary and secondary outcomes will be reported overall and by probability stratum. DISCUSSION: This innovative clinical trial will test the effectiveness and financial feasibility of using a precision health intervention to improve CRC screening completion in community health centers.

trial registrationNational Clinical Trial (NCT) Identifier: NCT03925883.

Indexed as

ColonoscopyColorectal NeoplasmsEarly Detection of CancerOccult BloodPatient CompliancePatient NavigationAgedCommunicationCommunity Health CentersCost-Benefit AnalysisFemaleHealth PromotionHumansMaleMiddle AgedMulticenter Studies as TopicColorectal cancer screeningFecal immunochemical testing (FIT)Patient navigationPrediction

Identifiers

PMID31881390
PMCPMC7254876
OpenAlexW2998548454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.