Evidence map›Paper›PMID 31880868›Full record

ArticleMicrobial biotechnology2020

Progress and challenges in engineering cyanobacteria as chassis for light-driven biotechnology.

Andrew Hitchcock, C Neil Hunter, Daniel P Canniffe

Open access · goldAbstract read
In one paragraph

Article in Microbial biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Article
  3. Improving productivity of citramalate from COBiotechnology for biofuels and bioproducts · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Life in biophotovoltaics systems.Frontiers in plant science · 2023
    Review
  12. Plant direct · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. GC/MS-basedMicrobial cell factories · 2022
    Article
  17. Insights into cyanobacterial alkane biosynthesis.Journal of industrial microbiology & biotechnology · 2022
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Andrew HitchcockDepartment of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.ORCID 0000-0001-6572-434X
C Neil HunterDepartment of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.ORCID 0000-0003-2533-9783
Daniel P CanniffeInstitute of Integrative Biology, University of Liverpool, Liverpool, UK.ORCID 0000-0002-5022-0437
University of Sheffield · GBUniversity of Liverpool · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M000265/1Biotechnology and Biological Sciences Research Council (BBSRC UK) BB/M000265/1
6 · The paper itself

Abstract

Cyanobacteria are prokaryotic phototrophs that, in addition to being excellent model organisms for studying photosynthesis, have tremendous potential for light-driven synthetic biology and biotechnology. These versatile and resilient microorganisms harness the energy of sunlight to oxidise water, generating chemical energy (ATP) and reductant (NADPH) that can be used to drive sustainable synthesis of high-value natural products in genetically modified strains. In this commentary article for the Synthetic Microbiology Caucus we discuss the great progress that has been made in engineering cyanobacterial hosts as microbial cell factories for solar-powered biosynthesis. We focus on some of the main areas where the synthetic biology and metabolic engineering tools in cyanobacteria are not as advanced as those in more widely used heterotrophic chassis, and go on to highlight key improvements that we feel are required to unlock the full power of cyanobacteria for future green biotechnology.

Indexed as

CyanobacteriaBiotechnologyMetabolic EngineeringPhotosynthesisSynthetic Biology

Identifiers

PMID31880868
PMCPMC7017823
OpenAlexW2996875961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.