Evidence map›Paper›PMID 31880395›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Versatile Glycosyl Sulfonates in β-Selective C-Glycosylation.

Jesse Ling, Clay S Bennett

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Preparation of ketonylScience advances · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mild Cu(OTf)The Journal of organic chemistry · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jesse LingTufts University, 62 Talbot Ave., Medford, MA, 02155, USA.
Clay S BennettTufts University, 62 Talbot Ave., Medford, MA, 02155, USA.ORCID 0000-0001-8070-4988
Tufts University · US

Funding

Reagent Control for Stereoselective Glycosylation ReactionsU01GM120414 · NIGMS · TUFTS UNIVERSITY MEDFORD · PI BENNETT, CLAY SAMUEL · 2016 to 2019
$1.5M
NIGMS NIH HHS U01 GM120414
6 · The paper itself

Abstract

C-Glycosides are both a common motif in many bioactive natural products and important glycoside mimetics. We demonstrate that activating a hemiacetal with a sulfonyl chloride, followed by treating the resultant glycosyl sulfonate with an enolate results in the stereospecific construction of β-linked C-glycosides. This reaction tolerates a range of acceptors and donors, including disaccharides. The resulting products can be readily derivatized into C-glycoside analogues of β-glycoconjugates, including C-disaccharide mimetics.

Indexed as

AlkylationDisaccharidesGlycoconjugatesGlycosidesGlycosylationMolecular StructureStereoisomerismSulfinic AcidsC-glycosideDisaccharidesGlycoconjugatesGlycosidesSulfinic Acidssulfonyl chloridecarbohydratesC-glycosidesglycoconjugatesglycosylationglycosyl sulfonates

Identifiers

PMID31880395
PMCPMC7054165
OpenAlexW2998675983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.