Evidence map›Paper›PMID 31880316›Full record

ArticleImmunology2020

Signalling lymphocyte activation molecule family member 9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection.

Timothy J Wilson, Simon Clare, Joseph Mikulin, Christopher M Johnson, Katherine Harcourt, Paul A Lyons, Gordon Dougan, Kenneth G C Smith

Open access · hybridAbstract read
In one paragraph

Article in Immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. SLAM Family Receptors in B Cell Chronic Lymphoproliferative Disorders.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Efficacy of bivalentHeliyon · 2022
    Article
  9. Article
  10. A simplified method for separating renal MPCs using SLAMF9.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Timothy J WilsonDepartment of Microbiology, Miami University, Oxford, OH, USA.ORCID 0000-0001-8403-9401
Simon ClareWellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
Joseph MikulinDepartment of Microbiology, Miami University, Oxford, OH, USA.
Christopher M JohnsonMRC Laboratory of Molecular Biology, Cambridge, UK.
Katherine HarcourtWellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
Paul A LyonsDepartment of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Gordon DouganWellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
Kenneth G C SmithDepartment of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.ORCID 0000-0003-3829-4326
University of Cambridge · GBWellcome Sanger Institute · GBMiami University · USMRC Laboratory of Molecular Biology · GB

Funding

Regulation of Type-I Interferon by SLAMF9R15AI138184 · NIAID · MIAMI UNIVERSITY OXFORD · PI WILSON, TIMOTHY JAMES · 2019 to 2019
$434k
Medical Research Council MC_U105184326Medical Research Council MR/L019027/1NIAID NIH HHS R15 AI138184Wellcome TrustWellcome Trust 206194
6 · The paper itself

Abstract

Signalling lymphocyte activation molecule family member 9 (SLAMF9) is an orphan receptor of the CD2/SLAM family of leucocyte surface proteins. Examination of SLAMF9 expression and function indicates that SLAMF9 promotes inflammation by specialized subsets of antigen-presenting cells. Within healthy liver and circulating mouse peripheral blood mononuclear cells, SLAMF9 is expressed on CD11b

Indexed as

AnimalsB-LymphocytesCell DifferentiationDendritic CellsGene Expression RegulationGranulocyte-Macrophage Colony-Stimulating FactorHost-Pathogen InteractionsHumansInterleukin-1betaLipopolysaccharidesLiverMacrophagesMiceMice, Inbred C57BLMice, KnockoutMonocytesGranulocyte-Macrophage Colony-Stimulating FactorIL1B protein, humanInterleukin-1betaLipopolysaccharidesSignaling Lymphocytic Activation Molecule FamilySLAMF9 protein, humanSlamf9 protein, mouseTumor Necrosis Factor-alphadendritic cellsinflammationmononuclear phagocytesSalmonellaSLAMF9

Identifiers

PMID31880316
PMCPMC7078004
OpenAlexW2997831287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.