Evidence map›Paper›PMID 31880315›Full record

ArticleBiometrics2020

ROC-guided survival trees and ensembles.

Yifei Sun, Sy Han Chiou, Mei-Cheng Wang

Abstract read
In one paragraph

Article in Biometrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Survival analysis using deep learning with medical imaging.The international journal of biostatistics · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yifei SunDepartment of Biostatistics, Columbia Mailman School of Public Health, New York, New York.ORCID 0000-0002-6961-5500
Sy Han ChiouDepartment of Mathematical Sciences, University of Texas at Dallas, Richardson, Texas.ORCID 0000-0003-2672-662X
Mei-Cheng WangDepartment of Biotatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.ORCID 0000-0002-0460-7956

Funding

Project 2 MeasurementU19AG033655 · NIA · JOHNS HOPKINS UNIVERSITY · PI JUAN TRONCOSO · 2014 to 2026
$51.5M
Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI Corinne Pettigrew · 2020 to 2026
$29.3M
Methods of reduced-cost designs for studying disease incidence and fatality risksR01HL122212 · NHLBI · UNIVERSITY OF WASHINGTON · PI CHAN, KWUN CHUEN GARY · 2014 to 2017
$2.2M
Statistical Methods for Survival and Recurrent Event Data in Clinical ResearchR01CA193888 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, CHIUNG-YU · 2015 to 2019
$1.7M
NCI NIH HHS R01 CA193888NHLBI NIH HHS R01 HL122212NIA NIH HHS P30 AG066507NIA NIH HHS U19 AG033655
6 · The paper itself

Abstract

Tree-based methods are popular nonparametric tools in studying time-to-event outcomes. In this article, we introduce a novel framework for survival trees and ensembles, where the trees partition the dynamic survivor population and can handle time-dependent covariates. Using the idea of randomized tests, we develop generalized time-dependent receiver operating characteristic (ROC) curves for evaluating the performance of survival trees. The tree-building algorithm is guided by decision-theoretic criteria based on ROC, targeting specifically for prediction accuracy. To address the instability issue of a single tree, we propose a novel ensemble procedure based on averaging martingale estimating equations, which is different from existing methods that average the predicted survival or cumulative hazard functions from individual trees. Extensive simulation studies are conducted to examine the performance of the proposed methods. We apply the methods to a study on AIDS for illustration.

Indexed as

AlgorithmsComputer SimulationROC Curveconcordance indexrisk predictionROC curvetime-dependent covariatetree-based method

Identifiers

PMID31880315
PMCPMC8491647

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.