ArticleMedicina oral, patologia oral y cirugia bucal2020
The recurrence of odontogenic keratocysts in pediatric patients is associated with clinical findings of Gorlin-Goltz Syndrome.
Article in Medicina oral, patologia oral y cirugia bucal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 11 citations in OpenAlex.
- Recurrent Metastatic Basal Cell Carcinomas of the Face in a Patient with Gorlin-Goltz Syndrome.Current oncology (Toronto, Ont.) · 2025Article
- Clinicopathological and molecular insights into odontogenic tumors associated with syndromes: A comprehensive review.World journal of experimental medicine · 2024Review
- Further Expanding the Mutational Spectrum of Gorlin Syndrome in Three Unrelated Families.Molecular syndromology · 2024Article
- Radiological evaluation of odontogenic keratocysts in patients with nevoid basal cell carcinoma syndrome: A review.The Saudi dental journal · 2023Review
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5 authors at 1 institution in 1 country.
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Abstract
backgroundOdontogenic keratocyst (OKC) is an odontogenic developmental cyst that presents distinct clinical behavior. This lesion has been described as dental cysts with keratinization since the 1930s, however the term OKC was established in 1956. This study aims to determine the frequency and features of OKC in children aged 0 to 14 years in an oral pathology service in Brazil. MATERIAL AND
methodsA retrospective study was performed to review cases of OKC in children diagnosed between 1986 and 2017. Clinical data were evaluated from medical records (gender, race, age, anatomical location, treatment, radiographic findings and follow-up).
resultsNinety-seven cases of OKC were diagnosed in a 31-year-period in all age groups and 10 were found in children (10.3%). Age ranged from 2 to 14 years (mean age=10.5±3.5), with 8 males and 2 females. The most frequent location was the anterior region of the mandible (n=4). Patients were predominantly asymptomatic. Moreover, in two children, clinical findings of Gorlin-Goltz Syndrome were observed. The most commonly used treatment was enucleation followed by curettage. In all cases of Gorlin-Goltz Syndrome were observed recurrences and occurrence of new keratocysts.
conclusionAlthough uncommon in pediatric patients, OKC should be considered a differential diagnosis in cases of osteolytic lesions in gnathic bones. Thus, the periodic assessment of children by dentists and pediatricians is essential to get a correct diagnosis and early treatment to avoid greater mutilation of these patients.
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