ArticleMedicina oral, patologia oral y cirugia bucal2020
Oral potentially malignant disorders: clinical-pathological study of 684 cases diagnosed in a Brazilian population.
Article in Medicina oral, patologia oral y cirugia bucal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- A Systematic Review of MicroRNA Signatures Associated with the Progression of Leukoplakia with and without Epithelial Dysplasia.Biomolecules · 2021Pooled it
- Characterization of Clinical and Histopathological Profiles of Oral Potentially Malignant Disorders With Oral Epithelial Dysplasia: Focus on Subepithelial Lymphoplasmacytic Infiltrate and Its Grading.Clinical and experimental dental research · 2026Article
- Use of Oral Rub and Rinse Technique for Oral Cancer Screening: Results from a Community-based Program in an LMIC.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Prognostic factors for recurrence and malignant transformation after treatment of oral epithelial dysplasia: A mixed cohort study.PloS one · 2025Article
- Viral Involvement in Oral Potentially Malignant Disorders: A Scoping Review.Cancer management and research · 2025Review
- Review
- Estimating the burden of care for oral potentially malignant disorders and oral cancer in Brazilian dental practice.Medicina oral, patologia oral y cirugia bucal · 2024Article
- A rural teledentistry care experience: a geriatric approach to assessing oral health status and treatment needs in older adults from a Mapuche community in Chile.Frontiers in public health · 2024Article
- Article
- Profiling risk factors of micro-invasive carcinoma within oral potentially malignant disorders: a cross-sectional study.Clinical oral investigations · 2020Article
- Prevalence of Human Papilloma virus in potentially malignant oral disorders is a risk factor for development of early dysplasia-A cytological investigation.Pakistan journal of medical sciencesArticle
- Clinicopathological features of oral potentially malignant disorders among tobacco users and nonusers.National journal of maxillofacial surgeryArticle
- Small Dysplastic Oral Leucoplakia in a Smoking Woman: a Case Report.Journal of oral & maxillofacial researchArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe frequency and distribution of oral potentially malignant disorders (OPMD) may vary among different populations. The aim of the present study was to evaluate the clinical-pathological characteristics of OPMD diagnosed in a Brazilian oral pathology laboratory over a period of 11 years. MATERIAL AND
methodsAll cases diagnosed as leukoplakia, speckled leukoplakia, erythroplakia, and actinic cheilitis from 2005 to 2015 were analyzed. Clinical information was obtained from laboratory forms and histological information was obtained from histological slides stained with hematoxylin and eosin.
resultsthe final sample was comprised of 684 cases, of which 292 were males and 392 were females. The mean age was 58 years. The anatomical site most often involved was the lateral border of the tongue (23%), followed by the lower lip (20%), and by the buccal mucosa/vestibule (18%). Leukoplakia accounted for 82% of the sample (564 cases). The mean size of the leukoplakia and speckled leukoplakia lesions was 13 mm (ranging from 1 to 100 mm) and 15 mm (ranging from 5 to 30 mm), respectively (p=0.460). Males reported smoking and drinking alcohol more frequently than females (p=0.001 and p<0.0001, respectively). In half of the cases, dysplasia was not histologically detected, while slight dysplasia was detected in 28% of the cases. The lesions from patients aged from 41 to 80 years presented moderate and severe dysplasia more often than lesions from patients in other age groups.
conclusionsOPMD were more common in females in their sixties. Females were more frequently affected in all anatomical sites, except for the lips. Leukoplakia lesions were the most common OPMD, followed by actinic cheilitis. The lateral border of the tongue was the most affected anatomical site. OPMD located in the floor of the mouth/sublingual mucosa and lesions from older patients presented severe epithelial dysplasia with greater frequency.
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