Evidence map›Paper›PMID 31880208›Full record

ArticleAutophagy2020

ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging.

Supawadee Sukseree, Uwe Yacine Schwarze, Reinhard Gruber, Florian Gruber, Maria Quiles Del Rey, Joseph D Mancias, John D Bartlett, Erwin Tschachler, Leopold Eckhart

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  11. Increased HepaticInternational journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Supawadee SuksereeResearch Division of Biology and Pathobiology of the Skin, Department of Dermatology, Medical University of Vienna , Vienna, Austria.ORCID 0000-0002-7011-9352
Uwe Yacine SchwarzeDepartment of Oral Biology, Medical University of Vienna , Vienna, Austria.ORCID 0000-0002-8954-0024
Reinhard GruberDepartment of Oral Biology, Medical University of Vienna , Vienna, Austria.ORCID 0000-0001-5400-9009
Florian GruberResearch Division of Biology and Pathobiology of the Skin, Department of Dermatology, Medical University of Vienna , Vienna, Austria.ORCID 0000-0003-1094-5641
Maria Quiles Del ReyDivision of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana-Farber Cancer Institute , Boston, MA, USA.
Joseph D ManciasDivision of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana-Farber Cancer Institute , Boston, MA, USA.
John D BartlettDivision of Biosciences, College of Dentistry, The Ohio State University , Columbus, OH, USA.ORCID 0000-0003-2052-6299
Erwin TschachlerResearch Division of Biology and Pathobiology of the Skin, Department of Dermatology, Medical University of Vienna , Vienna, Austria.ORCID 0000-0002-0248-1798
Leopold EckhartResearch Division of Biology and Pathobiology of the Skin, Department of Dermatology, Medical University of Vienna , Vienna, Austria.ORCID 0000-0002-5645-2036
Medical University of Vienna · ATDana-Farber Cancer Institute · USThe Ohio State University · US

Funding

Enamelysin Processing Mechanisms in AmelogenesisR01DE028297 · NIDCR · OHIO STATE UNIVERSITY · PI BARTLETT, JOHN D · 2019 to 2023
$2.7M
NIDCR NIH HHS R01 DE028297
6 · The paper itself

Abstract

The incisors of rodents comprise an iron-rich enamel and grow throughout adult life, making them unique models of iron metabolism and tissue homeostasis during aging. Here, we deleted

Indexed as

AgingAmeloblastsAnimalsAutophagyAutophagy-Related Protein 7Epithelial CellsEpitheliumFemaleFerritinsGene DeletionGreen Fluorescent ProteinsHomeostasisIncisorIronMaleMiceAtg7 protein, mouseAutophagy-Related Protein 7FerritinsGreen Fluorescent ProteinsIronSequestosome-1 ProteinSqstm1 protein, mouseAgingameloblastATG7autophagyepitheliumferritinhyperplasiaironsecretiontooth

Identifiers

PMID31880208
PMCPMC8386597
OpenAlexW2996837089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.