Evidence map›Paper›PMID 31880004›Full record

ArticleThe EMBO journal2020

Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation.

Christian Trötschel, Hussein Hamzeh, Luis Alvarez, René Pascal, Fedir Lavryk, Wolfgang Bönigk, Heinz G Körschen, Astrid Müller, Ansgar Poetsch, Andreas Rennhack and 5 more

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Soluble adenylyl cyclase in nonmammalian sperm is directly controlled by pH, not by HCOProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Design principles of ciliary signaling.Journal of cell science · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. NaInternational journal of molecular sciences · 2023
    Review
  7. Article
  8. Review
  9. CatSper Calcium Channels: 20 Years On.Physiology (Bethesda, Md.) · 2023
    Review
  10. Article
  11. Article
  12. In Silico Reconstruction of Sperm Chemotaxis.International journal of molecular sciences · 2021
    Article
  13. Selection of Boar Sperm by Reproductive Biofluids as Chemoattractants.Animals : an open access journal from MDPI · 2020
    Article
  14. Reconstruction of the birth of a male sex chromosome present in Atlantic herring.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. The CaThe Journal of biological chemistry · 2020
    Article
  16. A family of hyperpolarization-activated channels selective for protons.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Christian TrötschelFakultät für Biologie und Biotechnologie, Ruhr-Universität Bochum, Bochum, Germany.ORCID 0000-0002-9607-1123
Hussein HamzehCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.ORCID 0000-0002-3056-788X
Luis AlvarezCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
René PascalCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
Fedir LavrykCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
Wolfgang BönigkCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
Heinz G KörschenCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
Astrid MüllerCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
Ansgar PoetschFakultät für Biologie und Biotechnologie, Ruhr-Universität Bochum, Bochum, Germany.ORCID 0000-0002-7540-3475
Andreas RennhackCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
Long GuiDepartments of Cell Biology and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Daniela NicastroDepartments of Cell Biology and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Timo StrünkerCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.ORCID 0000-0003-0812-1547
Reinhard SeifertCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.
U Benjamin KauppCenter of Advanced European Studies and Research (caesar), Molecular Sensory Systems, Bonn, Germany.ORCID 0000-0002-0696-6397
Center of Advanced European Studies and Research · DEMarine Biological Laboratory · USRuhr University Bochum · DEThe University of Texas Southwestern Medical Center · US

Funding

Structure and Function of Complexes that Regulate Ciliary MotilityR01GM083122 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Daniela Nicastro · 2007 to 2026
$6.2M
Cancer Prevention and Research Institute of Texas (CPRIT) RP170644Cancer Prevention and Research Institute of Texas (CPRIT) RR140082Deutsche Forschungsgemeinschaft (DFG) SPP 1726NIGMS NIH HHS R01 GM083122
6 · The paper itself

Abstract

Cilia serve as cellular antennae that translate sensory information into physiological responses. In the sperm flagellum, a single chemoattractant molecule can trigger a Ca

Indexed as

ChemotaxisProteomicsSignal TransductionAnimalsArbaciaCalciumCiliaCyclic GMPElectron Microscope TomographyFlagellaGuanylate CyclaseMaleMass SpectrometrySpermatozoaCalciumCyclic GMPGuanylate Cyclaseciliumelectron tomographyfertilizationquantitative mass spectrometrysignaling

Identifiers

PMID31880004
PMCPMC7024835
OpenAlexW2998165936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.