Evidence map›Paper›PMID 31879985›Full record

ArticleNMR in biomedicine2020

On the magnetic field dependence of deuterium metabolic imaging.

Robin A de Graaf, Arjan D Hendriks, Dennis W J Klomp, Chathura Kumaragamage, Dimitri Welting, Catalina S Arteaga de Castro, Peter B Brown, Scott McIntyre, Terence W Nixon, Jeanine J Prompers and 1 more

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Combining DMI and [European radiology experimental · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. In vivoMagnetic resonance in medicine · 2025
    Article
  16. Human Brain Deuterium Metabolic Imaging at 7 T: Impact of Different [6,6'-Journal of magnetic resonance imaging : JMRI · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Robin A de GraafDepartment of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut.ORCID 0000-0002-6570-7010
Arjan D HendriksDepartment of Radiology, Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands.
Dennis W J KlompDepartment of Radiology, Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands.
Chathura KumaragamageDepartment of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut.
Dimitri WeltingDepartment of Radiology, Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands.
Catalina S Arteaga de CastroDepartment of Radiology, Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-1055-2672
Peter B BrownDepartment of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut.
Scott McIntyreDepartment of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut.
Terence W NixonDepartment of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut.
Jeanine J PrompersDepartment of Radiology, Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-4756-4474
Henk M De FeyterDepartment of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut.
Yale University · USUtrecht University · NL

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Deuterium metabolic imaging (DMI) of neurological diseaseR01EB025840 · NIBIB · YALE UNIVERSITY · PI ROBIN A DE GRAAF, Henk De Feyter · 2019 to 2026
$4.2M
Robust 3D MR spectroscopic imaging through multi-coil magnetic field shapingR01EB014861 · NIBIB · YALE UNIVERSITY · PI DE GRAAF, ROBIN A · 2012 to 2020
$3.3M
NCATS NIH HHS UL1 TR001863NIBIB NIH HHS R01 EB014861NIBIB NIH HHS R01 EB025840NIH HHS R01-EB014861NIH HHS R01-EB025840
6 · The paper itself

Abstract

Deuterium metabolic imaging (DMI) is a novel MR-based method to spatially map metabolism of deuterated substrates such as [6,6'-

Indexed as

Magnetic FieldsMagnetic Resonance ImagingAnimalsBrainCarbon-13 Magnetic Resonance SpectroscopyDeuteriumHumansPhantoms, ImagingRatsSignal-To-Noise RatioDeuteriumdeuterium metabolic imagingmagnetic field dependenceresolutionsensitivity

Identifiers

PMID31879985
PMCPMC7141779
OpenAlexW2998605141

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.