Evidence map›Paper›PMID 31879863›Full record

ArticleDrugs & aging2020

Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease.

Eveliina Lintula, Miia Tiihonen, Heidi Taipale, Anna-Maija Tolppanen, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen, Aleksi Hamina

Open access · hybridAbstract read
In one paragraph

Article in Drugs & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Eveliina LintulaSchool of Pharmacy, University of Eastern Finland, P.O.B 1627, 70211, Kuopio, Finland.
Miia TiihonenSchool of Pharmacy, University of Eastern Finland, P.O.B 1627, 70211, Kuopio, Finland. miia.tiihonen@uef.fi.ORCID http://orcid.org/0000-0002-5069-5045
Heidi TaipaleSchool of Pharmacy, University of Eastern Finland, P.O.B 1627, 70211, Kuopio, Finland.
Anna-Maija TolppanenSchool of Pharmacy, University of Eastern Finland, P.O.B 1627, 70211, Kuopio, Finland.
Antti TanskanenDepartment of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
Jari TiihonenDepartment of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
Sirpa HartikainenSchool of Pharmacy, University of Eastern Finland, P.O.B 1627, 70211, Kuopio, Finland.
Aleksi HaminaSchool of Pharmacy, University of Eastern Finland, P.O.B 1627, 70211, Kuopio, Finland.
University of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHip fractures are common among persons with Alzheimer's disease (AD), but problems in pain assessment may lead to insufficient analgesia after hospitalization.

objectiveWe investigated the prevalence of opioid use in the 6 months after discharge from hospital care due to hip fracture among community-dwellers with and without AD. SETTING AND

methodThe Medication use and Alzheimer's disease (MEDALZ) cohort was used for this study, consisting of all community-dwelling persons newly diagnosed with AD during 2005-2011 in Finland and their comparison persons without AD matched on age, sex, and region of residence at the time of AD diagnosis. Data were collected from nationwide healthcare registers.

main outcome measuresWe investigated opioid use versus non-use in persons with and without AD in the 6 months after discharge from hospital care due to hip fracture.

resultsAltogether 2342 persons with AD and 1615 persons without AD, discharged to community settings within ≤ 120 days after a hip fracture, were included. A higher percentage of persons with AD used opioids compared to those without AD, 39.5% [95% confidence interval (CI) 37.5-41.5] versus 31.2% (95% CI 28.9-33.5). Persons with AD used more frequently strong opioids during the first 3 months and buprenorphine during the 6-month period, and used weak opioids less frequently after the first month after discharge compared to those without AD.

conclusionsFrequent opioid use after hospital care due to hip fracture may indicate increased attention to pain among persons with AD. Nevertheless, the benefits and harms of opioid use should be evaluated regularly in community-dwelling older persons.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseAnalgesics, OpioidCohort StudiesFemaleHip FracturesHumansIndependent LivingMalePatient DischargeAnalgesics, Opioid

Identifiers

PMID31879863
PMCPMC7044157
OpenAlexW2997786418

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.