Evidence map›Paper›PMID 31879852›Full record

ReviewCNS drugs2020

Pharmacotherapy for Pediatric Convulsive Status Epilepticus.

Avantika Singh, Coral M Stredny, Tobias Loddenkemper

2 registry-linked trialsOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CNS drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04926844 phase2completednot on this mapstarted 2021, after this paper: background citation

Effectiveness of Combined Levetiracetam and Midazolam in Treatment of Generalized Convulsive Status Epilepticus in Children

TypeinterventionalSponsorSohag UniversityRan2021 to 2022Enrolled144ConditionsStatus Epilepticus, Generalized Convulsive Status Epilepticus, Status Epilepticus, Generalized, Status Epilepticus, Generalized ConvulsiveArmsLevetiracetam, Midazolam, Placebo
NCT05779657 phase2 / phase3completednot on this mapstarted 2023, after this paper: background citation

Efficacy of Combined Ketamine and Midazolam for Treatment of Generalized Convulsive Status Epilepticus in Children .

TypeinterventionalSponsorSohag UniversityRan2023 to 2024Enrolled144ConditionsGeneralized Convulsive Status EpilepticusArmsKetamine, Midazolam, Placebo
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Avantika SinghDivision of Epilepsy and Clinical Neurophysiology, Fegan 9, Department of Neurology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Coral M StrednyDivision of Epilepsy and Clinical Neurophysiology, Fegan 9, Department of Neurology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Tobias LoddenkemperDivision of Epilepsy and Clinical Neurophysiology, Fegan 9, Department of Neurology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA. tobias.loddenkemper@childrens.harvard.edu.
Boston Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Convulsive status epilepticus (CSE) is one of the most common pediatric neurological emergencies. Ongoing seizure activity is a dynamic process and may be associated with progressive impairment of gamma-aminobutyric acid (GABA)-mediated inhibition due to rapid internalization of GABA

Indexed as

AnimalsAnticonvulsantsChildHumansSeizuresStatus EpilepticusAnticonvulsants

Identifiers

PMID31879852
PMCPMC6982635
OpenAlexW2997327670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.