Evidence map›Paper›PMID 31879673›Full record

ReviewOpen forum infectious diseases2019

Sequelae of Lassa Fever: Postviral Cerebellar Ataxia.

Chiomah Ezeomah, Adeyi Adoga, Chikwe Ihekweazu, Slobodan Paessler, Irma Cisneros, Oyewale Tomori, David Walker

Open access · goldAbstract readReview
In one paragraph

Review in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Lassa fever vaccine candidates: A scoping review of vaccine clinical trials.Tropical medicine & international health : TM & IH · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chiomah EzeomahDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Adeyi AdogaDepartment of Otorhinolaryngology, Head and Neck Surgery, Jos University Teaching Hospital, University of Jos, Jos, Nigeria.
Chikwe IhekweazuNigerian Center for Disease Control, Federal Ministry of Health, Abuja, Nigeria.
Slobodan PaesslerDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Irma CisnerosDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Oyewale TomoriNational Lassa Fever Steering Committee, Federal Ministry of Health, Abuja, Nigeria.
David WalkerDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0002-3309-4360
The University of Texas Medical Branch at Galveston · USFederal Ministry of Health · NGUniversity of Jos · NG

Funding

Sequelae of Lassa FeverR01AI129198 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PAESSLER, SLOBODAN · 2018 to 2022
$3.9M
NIAID NIH HHS R01 AI129198
6 · The paper itself

Abstract

Lassa fever is a zoonotic disease endemic in some West African countries. It is exported to countries in America, Asia, and Europe. Antivirals against Lassa fever are important to provide a cure in patients with the disease and provide protection against it. In addition, due to the potential utilization of Lassa virus as a bioterrorism agent, vaccines against the disease can be utilized as a counterterrorism measure. Developing antiviral compounds and vaccines against the disease requires understanding of the pathogenesis of Lassa fever and its disease course, including the signs, symptoms, complications, and sequelae. An important sequela of Lassa fever is ataxia. A few cases of postviral ataxia following Lassa fever have been described in the literature. This review focuses on highlighting these cases, the gaps in scientific knowledge where further research is needed, and possible ways of diagnosing postviral ataxia after Lassa fever in resource-limited settings.

Indexed as

ataxiaLassa feverneurodegenerative disorderpostviralsequelae of Lassa fever

Identifiers

PMID31879673
PMCPMC6923636
OpenAlexW2992984096

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.