Evidence map›Paper›PMID 31879671›Full record

ArticleJournal of arthropod-borne diseases2019

Characterization of Glycoproteins of Native 19kDa C-Terminal Merozoite Surface Protein-1 from Native Antigen of

Sahar Tajik, Sedigheh Sadeghi, Ayda Iravani, Mitra Khalili, Mohammad Arjmand, Nassir-Ud Din, Farideh Vahabi, Hossein Feiz-Haddad, Behzad Lame-Rad, Saied Reza Naddaf and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of arthropod-borne diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sahar TajikDepartment of Biochemistry, Payame-Noor University, Tehran, Iran.
Sedigheh SadeghiDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Ayda IravaniDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Mitra KhaliliDepartment of Biochemistry, Payame-Noor University, Tehran, Iran.
Mohammad ArjmandDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Nassir-Ud DinInstitute of Bioinformatics, Lahore, Pakistan.
Farideh VahabiDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Hossein Feiz-HaddadDepartment of Parasitology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Behzad Lame-RadDepartment of Biochemistry, Payame-Noor University, Tehran, Iran.
Saied Reza NaddafDepartment of Parasitology, Pasteur Institute of Iran, Tehran, Iran.
Zahra ZamaniDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Pasteur Institute of Iran · IRPayame Noor University · IRAhvaz Jundishapur University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThe study was carried out at the Biochemistry Department of Pasteur Institute of Iran in the years 2015-2016. Large scale culture of

resultsThe purified protein gave a single band of 19kDa antigen as shown by silver staining of SDS-PAGE and a single bond in immunoblotting. Bioinformatics also confirmed the likelihood of the presence of glycans on the antigen.

conclusionThe presence of N and O-glycoproteins were detected by Q proteome kit. This work was done on the ring stage, and earlier workers confirmed the presence of glycoproteins on MSP1 in the other stages. This glycosylation is present in all stages, and maybe incomplete protection elicited by recombinant MSP1 antigens is due to lack of N and O-glycoproteins.

Indexed as

C-terminal 19kDaGlycoproteinsMerozoite surface protein1Plasmodium falciparum

Identifiers

PMID31879671
PMCPMC6928381
OpenAlexW2979312556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.