ArticleJournal of family medicine and primary care2019
Predictive value of ultrasound imaging in differentiating benign from malignant breast lesions taking biopsy results as the standard.
Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Efficacy of ultrasonography and mammography in detecting features of breast cancer.Journal of family medicine and primary care · 2025Article
- Article
- A rare phenotype of breast hydatid cyst causing misdiagnosis and unnecessary intervention: a case report.Radiology case reports · 2021Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreast lesions (BLs) are abnormal swellings within the breast. The importance lies in need to exclude breast cancer.
objectiveDue to the role of ultrasound (US) imaging in evaluating of BLs, this study was conducted to evaluate the predictive value of US imaging for differentiating benign from malignant BLs and to assess the need of biopsy in BLs.
methodA retrospective review of diagnostic results of 134 patients with BLs. All patients underwent breast US imaging and US-guided biopsy for cytology or histopathology. The results of both were compared.
resultsOut of 134 patients were included in this study, the mean age was 38.45 ± 15.82 years (range, 18-90 years), and all patients were female. BLs were benign in 99 cases (73.9%) and malignant in 35 cases (26.1%). Among 98 patients with BLs diagnosed benign with US, 96.9% were confirmed benign with biopsy results and only 3.1% were malignant. The overall sensitivity of US imaging for discriminating of benign BLs was 95.95%, with a specificity of 91.42%, and positive predictive value of 96.94%. The results revealed strong compatibility between diagnoses by US imaging and biopsy results (
conclusionUS imaging is a highly valuable imaging method in differentiating benign from malignant BLs. It usually predicts the benign nature of BLs with excellent diagnostic accuracy. US-guided fine-needle aspiration and core-needle biopsies are not necessary in most cases of BLs.
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