Evidence map›Paper›PMID 31879641›Full record

ArticleJournal of family medicine and primary care2019

Clinico-hematological study of pancytopenia: A single-center experience from north Himalayan region of India.

Harish Chandra, Arvind K Gupta, Uttam K Nath, Neha Singh, Utpal Kumar, Sanjeev Kishore

Open access · goldAbstract read
In one paragraph

Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Harish ChandraDepartment of Pathology and Lab Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Arvind K GuptaDepartment of Pathology and Lab Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Uttam K NathDepartment of Medical Oncology and Hematology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Neha SinghDepartment of Pathology and Lab Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Utpal KumarDepartment of Pathology and Lab Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Sanjeev KishoreDepartment of Pathology and Lab Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences Rishikesh · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancytopenia, an important hematological presentation is associated with different causes, which may vary in different regions. Uttarakhand, a north Himalayan state of India lacks studies of pancytopenia and the prevalent causes present in this region. Therefore, the present study was conducted to study the clinico-hematological profile of pancytopenia in a tertiary care center in the Uttarakhand, a north Himalayan state of India. It was also intended to study if these causes showed any variation from other studies done in different regions of India. MATERIALS AND

methodsThe present observational study was conducted in a tertiary care institute situated in Uttarakhand state of India over a period of 1 year and 8 month from June 2017 to Feb 2019 including all the cases of pancytopenia.

resultsThe most common cause of pancytopenia was megaloblastic anemia (25%), followed by aleukemic leukemia and hypoplastic/aplastic anemia (19.1% each). Visceral leishmaniasis also constituted an important cause of pancytopenia in this study (11.7%).

conclusionThe study concludes that megaloblastic anemia and aleukemic leukemia are the most common cause of pancytopenia. Although leishmaniasis is considered to be non-endemic in this region, it constitutes an important cause of pancytopenia here. The clinicians, especially the physicians practicing the primary care and pathologists, should be aware of the different causes of pancytopenia present in this Himalayan region of India; therefore, delay in diagnosis can be prevented along with unnecessary investigations.

Indexed as

Aleukemic leukemiaaplastic anemialeishmaniasismegaloblastic anemiapancytopenia

Identifiers

PMID31879641
PMCPMC6924218
OpenAlexW2996232923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.