Evidence map›Paper›PMID 31879529›Full record

ArticleTheranostics2019

Point-of-care cervical cancer screening using deep learning-based microholography.

Divya Pathania, Christian Landeros, Lucas Rohrer, Victoria D'Agostino, Seonki Hong, Ismail Degani, Maria Avila-Wallace, Misha Pivovarov, Thomas Randall, Ralph Weissleder and 3 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Artificial intelligence and visual inspection in cervical cancer screening.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Article
  13. Engineering Innovative Interfaces for Point-of-Care Diagnostics.Current opinion in colloid & interface science · 2023
    Review
  14. Article
  15. Review
  16. Review
  17. Review
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Divya PathaniaCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Christian LanderosCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Lucas RohrerCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Victoria D'AgostinoCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Seonki HongCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Ismail DeganiCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Maria Avila-WallaceDepartment of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA.
Misha PivovarovCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Thomas RandallDepartment of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA.
Ralph WeisslederCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Hakho LeeCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Hyungsoon ImCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Cesar M CastroCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Massachusetts General Hospital · USCenter for Systems Biology · USHarvard University · USMassachusetts Institute of Technology · US

Funding

Early Detection through Novel OCEAN Technology - Ovarian Cancer Exosomal Analysis with NanoplasmonicsU01CA233360 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CASTRO, CESAR M, DINULESCU, DANIELA M · 2018 to 2022
$3.5M
Clinical platform for high-throughput analyses of extracellular vesiclesR01CA229777 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO, SKOG, JOHAN · 2018 to 2022
$3.2M
Smartphone for molecular cancer diagnostic in AfricaUH3CA202637 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHABNER, BRUCE ALLAN, WEISSLEDER, MD, PHD, RALPH · 2018 to 2020
$2.9M
Novel Nano-Plasmonic Technology for Quantitative Analysis of Cancer ExosomesR00CA201248 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI IM, HYUNGSOON · 2017 to 2019
$968k
Novel nano-plasmonic technology for quantitative analysis of cancer exosomesK99CA201248 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI IM, HYUNGSOON · 2015 to 2016
$329k
NCI NIH HHS K99 CA201248NCI NIH HHS R00 CA201248NCI NIH HHS R01 CA229777NCI NIH HHS U01 CA233360NCI NIH HHS UH3 CA202637
6 · The paper itself

Abstract

Most deaths (80%) from cervical cancer occur in regions lacking adequate screening infrastructures or ready access to them. In contrast, most developed countries now embrace human papillomavirus (HPV) analyses as standalone screening; this transition threatens to further widen the resource gap.

Indexed as

Deep LearningCervix UteriEarly Detection of CancerFemaleHuman papillomavirus 16Human papillomavirus 18HumansPapillomaviridaePoint-of-Care SystemsUterine Cervical NeoplasmsCervical cancerdeep learningglobal oncologymicroholographypoint-of-care screening

Identifiers

PMID31879529
PMCPMC6924258
OpenAlexW2994323711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.