ArticleJournal of orthopaedics
Expression pattern of Syndecan-1 and HSP-70 in hip tissue of patients with osteoarthritis.
Article in Journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- MAPK Pathway Activation Patterns in the Synovium Reveal ERK1/2 and EGFR as Key Players in Osteoarthritis.Biomedicines · 2025Article
- WNT Signaling Factors as Potential Synovial Inflammation Moderators in Patients with Hip Osteoarthritis.Biomedicines · 2025Article
- Heat shock proteins in osteoarthritis: molecular mechanisms, pathogenic roles, and therapeutic opportunities.Frontiers in immunology · 2025Review
- Immunofluorescence Analysis of NF-kB and iNOS Expression in Different Cell Populations during Early and Advanced Knee Osteoarthritis.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe investigated the expression of Syndecan-1 and HSP-70 in synovial, chondral and subchondral tissue in the hips of patients with osteoarthritis (OA).
methodsTotal hip arthroplasty was performed on 6 patients and 3 controls. Patients were divided into two groups according to disease severity. The tissues were immunohistochemically analyzed.
resultsCartilage and subchondral tissue in patients with severe OA contained abundant positive cells with a mean positive percentage of 94,51 ± 5% and 78,95 ± 14% for Syndecan-1 and 94,42 ± 5% and 75,67 ± 17% for HSP-70, respectively.
conclusionIn conclusion, HSP-70 and Syndecan-1 might play a role in the onset and regulation of OA in the hip.
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Registered trials
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