ArticleProceedings of the National Academy of Sciences of the United States of America2020
Quantifying the flux as the driving force for nonequilibrium dynamics and thermodynamics in non-Michaelis-Menten enzyme kinetics.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Quantifying Landscape and Flux from Single-Cell Omics: Unraveling the Physical Mechanisms of Cell Function.JACS Au · 2025Review
- Uncovering underlying physical principles and driving forces of cell differentiation and reprogramming from single-cell transcriptomics.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Understanding underlying physical mechanism reveals early warning indicators and key elements for adaptive infections disease networks.PNAS nexus · 2024Article
- Approximate Bayesian computation for inferring Waddington landscapes from single-cell data.Royal Society open science · 2024Article
- Identifying the active sites in unequal iron-nitrogen single-atom catalysts.Nature communications · 2023Article
- Inferring entropy production rate from partially observed Langevin dynamics under coarse-graining.Physical chemistry chemical physics : PCCP · 2022Article
- Perspectives on the landscape and flux theory for describing emergent behaviors of the biological systems.Journal of biological physics · 2022Review
- Physical bioenergetics: Energy fluxes, budgets, and constraints in cells.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Improved bounds on entropy production in living systems.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The driving force for active physical and biological systems is determined by both the underlying landscape and nonequilibrium curl flux. While landscape can be experimentally quantified from the histograms of the collected real-time trajectories of the observables, quantifying the experimental flux remains challenging. In this work, we studied the single-molecule enzyme dynamics of horseradish peroxidase with dihydrorhodamine 123 and hydrogen peroxide (H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.