Evidence map›Paper›PMID 31879285›Full record

SynthesisJournal of neurology, neurosurgery, and psychiatry2020

Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis.

Wei Xu, Chen-Chen Tan, Juan-Juan Zou, Xi-Peng Cao, Lan Tan

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of neurology, neurosurgery, and psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 177 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
177citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

177 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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  7. Effect of Excessive Daytime Sleepiness and Long Sleep Duration on All Cause Dementia: A Systematic Review and Meta-analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
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  13. Insomnia disorder with objective short sleep duration (ISS) phenotype and cognitive performance: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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  19. Smoking Interacts WithBiological psychiatry global open science · 2026
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  20. Presurgical Sleep-Wake Disturbance and Postoperative Delirium: A Prospective Cohort Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
    Article

117 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei XuNeurology Department, Qingdao Municipal Hospital Group, Qingdao University, Qingdao, Shandong, China 1037219730@qq.com.ORCID 0000-0002-3310-5875
Chen-Chen TanNeurology Department, Qingdao Municipal Hospital Group, Qingdao University, Qingdao, Shandong, China.
Juan-Juan ZouDepartment of Otorhinolaryngology, Qilu Hospital of Shandong University; NHC Key Laboratory of Otorhinolaryngology, Shandong University, Jinan, China.
Xi-Peng CaoClinical Research Center, Qingdao Municipal Hospital Group, Qingdao, Shandong, China.
Lan TanNeurology Department, Qingdao Municipal Hospital Group, Qingdao University, Qingdao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo conduct an updated systematic review and meta-analysis of association between sleep and all-cause cognitive disorders.

methodsPubMed and EMBASE were searched from inception to 18 February 2019. Cohort studies exploring longitudinal associations of sleep with cognitive decline or dementia were included. The multivariable-adjusted effect estimates were pooled by random-effects models, with credibility assessment. The robust error meta-regression model was used to conduct the dose-response meta-analysis for sleep duration.

results11 155 reports were searched and 51 eligible cohorts with 15 sleep problems were included for our meta-analyses. Ten types of sleep conditions or parameters, including six (insomnia, fragmentation, daytime dysfunction, prolonged latency, rapid eye movement sleep behaviour disorder and excessive time in bed) with moderate-to-high levels of evidence, were linked to higher risk of all-cause cognitive disorders. Furthermore, a U-shaped relationship was revealed for the associations with sleep duration.

conclusionsSleep management might serve as a promising target for dementia prevention.

Indexed as

Cognitive DysfunctionDementiaHumansSleep Wake DisordersCognitive declineDementiaMeta-analysisSleepSystematic review

Identifiers

PMID31879285
PMCPMC7035682

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.