Evidence map›Paper›PMID 31879014›Full record

ArticleBiochemical and biophysical research communications2020

Unleashing shear: Role of intercellular traction and cellular moments in collective cell migration.

Neel G Patel, Alyson Nguyen, Ningyong Xu, Shivani Ananthasekar, Diego F Alvarez, Troy Stevens, Dhananjay T Tambe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemical and biophysical research communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Conserved physical mechanisms of cell and tissue elongation.Development (Cambridge, England) · 2024
    Review
  4. Article
  5. Article
  6. Marangoni effect and cell spreading.European biophysics journal : EBJ · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neel G PatelWilliam B. Burnsed, Jr. Department of Mechanical Engineering, College of Engineering, University of South Alabama, Mobile, AL, USA.
Alyson NguyenDepartment of Biomedical Sciences, Pat Capps Covey College of Allied Health Professions, University of South Alabama, Mobile, AL, USA.
Ningyong XuDepartment of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, USA; Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
Shivani AnanthasekarSchool of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Diego F AlvarezDepartment of Physiology & Pharmacology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX, USA.
Troy StevensDepartment of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, USA; Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
Dhananjay T TambeWilliam B. Burnsed, Jr. Department of Mechanical Engineering, College of Engineering, University of South Alabama, Mobile, AL, USA; Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA; Department of Pharmacology, College of Medicine, University of South Alabama, Mobile, AL, USA. Electronic address: dtambe@southalabama.edu.

Funding

T-type Calcium Channels and von Willebrand Factor ReleaseP01HL066299 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI ALVAREZ, DIEGO F. · 2001 to 2022
$34.6M
Store-operated calcium entry: lung endothelial permeabilityR37HL060024 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI STEVENS, TROY · 2010 to 2019
$3.9M
Caspase-1, the Microvascular Endothelium, and InfectionR01HL118334 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI ALVAREZ, DIEGO F., AUDIA, JONATHON PETER · 2015 to 2019
$2.0M
TRPC4-DEPENDENT CYTOSOLIC CALCIUM SIGNALS COORDINATE INTERENDOTHELIAL FORCES THAT ELICIT GAP FORMATIONF32HL144040 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI XU, NINGYONG · 2018 to 2020
$167k
NHLBI NIH HHS F32 HL144040NHLBI NIH HHS P01 HL066299NHLBI NIH HHS R01 HL118334NHLBI NIH HHS R37 HL060024
6 · The paper itself

Abstract

In the field of endothelial biology, the term "shear forces" is tied to the forces exerted by the flowing blood on the quiescent cells. But endothelial cells themselves also exert physical forces on their immediate and distant neighbors. Specific factors of such intrinsic mechanical signals most relevant to immediate neighbors include normal (F

Indexed as

Cell MovementAnimalsCell ShapeExtracellular SpaceRatsShear Strength

Identifiers

PMID31879014
PMCPMC6957749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.