Evidence map›Paper›PMID 31878876›Full record

ArticleBMC geriatrics2019

Post-stroke patients with moderate function have the greatest risk of falls: a National Cohort Study.

Wycliffe E Wei, Deirdre A De Silva, Hui Meng Chang, Jiali Yao, David B Matchar, Sherry H Y Young, Siew Ju See, Gek Hsiang Lim, Ting Hway Wong, Narayanaswamy Venketasubramanian

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In one paragraph

Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Corticospinal Responses Following Gait-Specific Training in Stroke Survivors: A Systematic Review.International journal of environmental research and public health · 2022
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  12. An exploration of serious falls after stroke using a large international stroke rehabilitation database.International journal of stroke : official journal of the International Stroke Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wycliffe E WeiHealth Services Research Unit, Singapore General Hospital, Level 4, 226 Outram Road, Singapore, 169039, Singapore.
Deirdre A De SilvaDepartment of Neurology (Singapore General Hospital Campus), National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Hui Meng ChangDepartment of Neurology (Singapore General Hospital Campus), National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Jiali YaoSaw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, #10-01, Singapore, 117549, Singapore.
David B MatcharHealth Services & Systems Research, Duke-National University of Singapore Medical School, Singapore, 8 College Road, Singapore, 169857, Singapore.
Sherry H Y YoungDepartment of Rehabilitation Medicine, Changi General Hospital, 2 Simei Street 3, Singapore, 529889, Singapore.
Siew Ju SeeDepartment of Neurology (Singapore General Hospital Campus), National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Gek Hsiang LimHealth Promotion Board, 3 Second Hospital Avenue, Singapore, 168937, Singapore.
Ting Hway WongDuke-NUS Medical School, Singapore, 8 College Road, Singapore, 169857, Singapore. wong.th@doctors.org.uk.ORCID 0000-0001-9234-4529
Narayanaswamy VenketasubramanianRaffles Neuroscience Centre, Raffles Hospital, Level 9, 585 North Bridge Road, Singapore, 188770, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke patients have increased risks of falls. We examined national registry data to evaluate the association between post-stroke functional level and the risk of low falls among post-stroke patients.

methodsThis retrospective cohort study analyzed data from national registries to examine the risk factors for post-stroke falls. Data for patients who suffered ischemic strokes and survived the index hospital admission was obtained from the Singapore National Stroke Registry and matched to the National Trauma Registry, from 2011 to 2015. The primary outcome measure was a low fall (fall height ≤ 0.5 m). Competing risk analysis was performed to examine the association between functional level (by modified Rankin score [mRS] at discharge) and the risk of subsequent low falls.

resultsIn all, 2255 patients who suffered ischemic strokes had recorded mRS. The mean age was 66.6 years and 58.5% were men. By the end of 2015, 54 (2.39%) had a low fall while 93 (4.12%) died. After adjusting for potential confounders, mRS was associated with fall risk with an inverted U-shaped relationship. Compared to patients with a score of zero, the sub-distribution hazard ratio (SHR) increased to a maximum of 3.42 (95%CI:1.21-9.65, p = 0.020) for patients with a score of 2. The SHR then declined to 2.45 (95%CI:0.85-7.12, p = 0.098), 2.86 (95%CI:0.95-8.61, p = 0.062) and 1.93 (95%CI:0.44-8.52, p = 0.38) for patients with scores of 3, 4 and 5 respectively.

conclusionsAn inverted U-shaped relationship between functional status and fall risk was observed. This is consistent with the complex interplay between decreasing mobility (hence decreased opportunity to fall) and increasing susceptibility to falls. Fall prevention intervention could be targeted accordingly. (263 words).

Indexed as

RegistriesAccidental FallsAgedAged, 80 and overCohort StudiesFemaleHospitalizationHumansMaleMiddle AgedPatient DischargeRecovery of FunctionRetrospective StudiesRisk FactorsSingaporeStrokeFallsFunctionModified Rankin scaleStroke

Identifiers

PMID31878876
PMCPMC6933903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.