Evidence map›Paper›PMID 31878204›Full record

ArticleInternational journal of molecular sciences2019

Hyperoside Induces Breast Cancer Cells Apoptosis via ROS-Mediated NF-κB Signaling Pathway.

Jinxia Qiu, Tao Zhang, Xinying Zhu, Chao Yang, Yaxing Wang, Ning Zhou, Bingxin Ju, Tianhong Zhou, Ganzhen Deng, Changwei Qiu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 144 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Advances in quercetin-based therapeutics for breast cancer: natural, synthetic, and nanotechnology-driven approaches.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. The Therapeutic Potential ofMolecules (Basel, Switzerland) · 2025
    Article
  10. Polydatin: A natural compound with multifaceted anticancer properties.Journal of traditional and complementary medicine · 2025
    Review
  11. LC-HRMS/MS-Guided Profiling and Biological Evaluation ofMolecules (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. The Discovery of Potential Repellent Compounds forInternational journal of molecular sciences · 2025
    Article
  18. Review
  19. Plants (Basel, Switzerland) · 2025
    Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jinxia QiuDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0002-0048-6114
Tao ZhangDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Xinying ZhuDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Chao YangDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Yaxing WangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Ning ZhouDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Bingxin JuDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Tianhong ZhouDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Ganzhen DengDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Changwei QiuDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0002-7389-9534
Huazhong Agricultural University · CN

Funding

the National Major Project for Breeding of Transgenic Pig 2016ZX08006-002
6 · The paper itself

Abstract

Hyperoside (quercetin 3-

Indexed as

AnimalsApoptosisBreast NeoplasmsCell LineCell Line, TumorCell SurvivalFemaleHumansMCF-7 CellsMiceNF-kappa BQuercetinReactive Oxygen SpeciesSignal TransductionSincalideWound HealinghyperosideNF-kappa BQuercetinReactive Oxygen SpeciesSincalideapoptosisbreast cancerhyperosidenuclear transcription factor-κB (NF-κB)ROS

Identifiers

PMID31878204
PMCPMC6981893
OpenAlexW2997519067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.