ReviewMolecules (Basel, Switzerland)2019
Cinnamic Acid Conjugates in the Rescuing and Repurposing of Classical Antimalarial Drugs.
Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Enantioseparation of proton pump inhibitors using multimodal chiral cation exchangers.Analytical and bioanalytical chemistry · 2026Article
- Non-solvent cinnamic acid-based gel patch for transdermal drug delivery.Journal of advanced research · 2026Article
- Thymol Derivatives as Antimalarial Agents: Synthesis, Activity AgainstBiomedicines · 2026Article
- Practical and Efficient Synthesis of (Molecules (Basel, Switzerland) · 2025Article
- Article
- Properties and medical applications of the Euphorbiaceae family and their bioproducts: a patent review.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Quinoline conjugates for enhanced antimalarial activity: a review on synthesis by molecular hybridization and structure-activity relationship (SAR) investigation.American journal of translational research · 2025Review
- A Review of Cinnamic Acid's Skeleton Modification: Features for Antibacterial-Agent-Guided Derivatives.Molecules (Basel, Switzerland) · 2024Review
- Cinnamic Acid and Caffeic Acid Effects on Gastric Tight Junction Proteins Analyzed inMembranes · 2024Article
- Article
- Preclinical evaluation of antimalarial activity of CPF-1 formulation as an alternative choice for the treatment of malaria.BMC complementary medicine and therapies · 2023Article
- Improving the Antimycobacterial Drug Clofazimine through Formation of Organic Salts by Combination with Fluoroquinolones.International journal of molecular sciences · 2023Article
- Editorial: Antimalarial chemotherapy in the XXIst century.Frontiers in pharmacology · 2022Article
- Production ofInternational journal of molecular sciences · 2021Article
- Design, Synthesis and Anticancer Evaluation of Substituted Cinnamic Acid Bearing 2-Quinolone Hybrid Derivatives.Molecules (Basel, Switzerland) · 2021Article
- Myeloperoxidase Inhibitory and Antioxidant Activities of (Pharmaceuticals (Basel, Switzerland) · 2021Article
- Biological Activities and ADMET-Related Properties of Novel Set of Cinnamanilides.Molecules (Basel, Switzerland) · 2020Article
- Recycling Old Antibiotics with Ionic Liquids.Antibiotics (Basel, Switzerland) · 2020Review
- Alkyl and Aryl Derivatives Based onMolecules (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
Cinnamic acids are compounds of natural origin that can be found in many different parts of a wide panoply of plants, where they play the most diverse biological roles, often in a conjugated form. For a long time, this has been driving Medicinal Chemists towards the investigation of the therapeutic potential of natural, semi-synthetic, or fully synthetic cinnamic acid conjugates. These efforts have been steadily disclosing promising drug leads, but a wide chemical space remains that deserves to be further explored. Amongst different reported approaches, the combination or conjugation of cinnamic acids with known drugs has been addressed in an attempt to produce either synergistic or multi-target action. In this connection, the present review will focus on efforts of the past decade regarding conjugation with cinnamic acids as a tool for the rescuing or the repurposing of classical antimalarial drugs, and also on future perspectives in this particular field of research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.